Results 61 to 70 of about 4,362,153 (359)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Effect of visual impairment on driving [PDF]

, 1994
The aim of the study was to determine the effect on driving of restricting vision. This was undertaken by comparing the driving performance of young, normal subjects under conditions of simulated visual impairment with a baseline condition.
Wood, Joanne M., Joanne M. Wood, Rod Troutbeck, Troutbeck, Rodney J.   +3 more
core   +1 more source

Area of the cone interdigitation zone in healthy Chinese adults and its correlation with macular volume

BMC Ophthalmology, 2018
Background Numerous studies have suggested that the integrity of the cone interdigitation zone (IZ) could be considered to be a marker of photoreceptor damage and its recovery. However, little is known about the IZ in healthy eyes.
Ruiping Gu, Guohua Deng, Yi Jiang, Chunhui Jiang, Gezhi Xu   +4 more
doaj   +1 more source

Activation of the GABA-alpha receptor by berberine rescues retinal ganglion cells to attenuate experimental diabetic retinopathy

Frontiers in Molecular Neuroscience, 2022
PurposeThe aim of this study was to investigate the role and mechanism of berberine (BBR) in the protection of injured retinal ganglion cells (RGCs) in diabetic retinopathy (DR).MethodsExperimental diabetic retinopathy rat model was successfully induced ...
Wangyi Fang, Wangyi Fang, Wangyi Fang, Xiaojing Huang, Kaicheng Wu, Kaicheng Wu, Yuan Zong, Yuan Zong, Jian Yu, Jian Yu, Huan Xu, Huan Xu, Jiemei Shi, Jiemei Shi, Jiaojiao Wei, Jiaojiao Wei, Xujiao Zhou, Xujiao Zhou, Xujiao Zhou, Chunhui Jiang, Chunhui Jiang   +20 more
doaj   +1 more source

Prevalence, Risk Factors, and Impact of Myopic Macular Degeneration on Visual Impairment and Functioning Among Adults in Singapore.

Investigative Ophthalmology and Visual Science, 2018
Purpose To determine the prevalence, risk factors, and impact of myopic macular degeneration (MMD) on visual impairment and functioning among adults in Singapore.
Yee-Ling Wong, C. Sabanayagam, Yang Ding, C. Wong, A. Yeo, Y. Cheung, G. Cheung, A. Chia, K. Ohno-Matsui, T. Wong, Jie-Jin Wang, Ching-Yu Cheng, Quan V. Hoang, E. Lamoureux, S. Saw   +14 more
semanticscholar   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Hospital prevalence of visual of visual impairment caused by diabetic retinopathy [PDF]

, 2015
PurposeTo investigate cases of visual impairment caused by diabetic retinopathy (DR) in a hospital population.MethodsAs part of an observational study to estimate the prevalence and costs of visual impairment in Portugal (PCVIP study), clinical records ...
Perestrelo, Sara P.,, Macedo, António Filipe,, Rocha De Sousa, Amandio,, Lima-Ramos, Pedro,, Baptista, António M.,, Santana, Rui,, Tavares-Ferreira, Joao,   +6 more
core   +1 more source

Cytokine profiles in the aqueous humor of uveal melanoma: implications for tumor progression and radiation response

Frontiers in Medicine
PurposeThis study aimed to investigate the cytokine profile in the aqueous humor of uveal melanoma (UM) and explore the role of cytokines in tumor progression and radiation response.MethodsAqueous humor samples were collected from patients with UM who ...
Jie Ding, Jie Ding, Han Yue, Han Yue, Binbin Xu, Binbin Xu, Lianyao Shi, Jie Guo, Jie Guo, Jiang Qian, Jiang Qian   +10 more
doaj   +1 more source

Replication of the Association Between Keratoconus and Polymorphisms in PNPLA2 and MAML2 in a Han Chinese Population

Frontiers in Genetics, 2020
Keratoconus (KC) is a complex ocular disease that is affected by both genetic and non-genetic triggers. A recent genome-wide association study (GWAS) identified a genome-wide significant locus for KC in the region of PNPLA2 (rs61876744), as well as a ...
Jing Zhang, Jing Zhang, Jing Zhang, Yue Li, Yue Li, Yue Li, Yiqin Dai, Yiqin Dai, Yiqin Dai, Jianjiang Xu, Jianjiang Xu, Jianjiang Xu   +11 more
doaj   +1 more source

Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort

Scientific Reports, 2018
The association of visual impairment and depression has been investigated in several studies based on a cross-sectional design, which cannot delineate temporal relationships.
H. Choi, Min Joung Lee, Sang-Mok Lee
semanticscholar   +1 more source