Results 71 to 80 of about 4,116,225 (362)

Pre-treatment With Ranibizumab Aggravates PDT Injury and Alleviates Inflammatory Response in Choroid-Retinal Endothelial Cells

Frontiers in Cell and Developmental Biology, 2020
Polypoidal choroidal vasculopathy (PCV) is the predominant subtype of exudative age-related macular degeneration in Asians. Although photodynamic therapy (PDT) is widely used for PCV treatment, its long-term beneficial effects are unsatisfactory ...
Yang Liu, Yang Liu, Min Zhu, Min Zhu, Ruowen Gong, Ruowen Gong, Xin Wang, Xin Wang, Lei Li, Lei Li, Gezhi Xu, Gezhi Xu   +11 more
doaj   +1 more source

The profiles and clinical significance of extraocular muscle-expressed lncRNAs and mRNAs in oculomotor nerve palsy

Frontiers in Molecular Neuroscience, 2023
IntroductionOculomotor nerve palsy (ONP) arises from primary abnormalities in the central neural pathways that control the extraocular muscles (EOMs).
Lianqun Wu, Lianqun Wu, Lianqun Wu, Mingsu Shi, Mingsu Shi, Mingsu Shi, Yu Liang, Yu Liang, Yu Liang, Jiaqiu Huang, Jiaqiu Huang, Jiaqiu Huang, Weiyi Xia, Weiyi Xia, Weiyi Xia, Hewei Bian, Hewei Bian, Hewei Bian, Qiao Zhuo, Qiao Zhuo, Qiao Zhuo, Chen Zhao, Chen Zhao, Chen Zhao   +23 more
doaj   +1 more source

Prevelence and causes of visual impairment and blindness in older adults in an area of India with a high cataract surgical rate.

, 2010
BACKGROUND: The cataract surgical rate (CSR) in Gujarat, India is reported to be above 10,000 per million population. This study was conducted to investigate the prevalence and causes of vision impairment/blindness among older adults in a high CSR area ...
Ellwein, Leon B, John, Neena, Murthy, Gudlavalleti VS, Pokharel, Gopal, Vashist, Praveen   +4 more
core   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Direct and indirect effects of attention and visual function on gait impairment in Parkinson's disease: influence of task and turning [PDF]

, 2017
Gait impairment is a core feature of Parkinson's disease (PD) which has been linked to cognitive and visual deficits, but interactions between these features are poorly understood.
Delicato, Louise S., Foxe, John, Galna, Brook, Lord, Sue, Rochester, Lynn, Stuart, Sam   +5 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

SHP-2-Induced Activation of c-Myc Is Involved in PDGF-B-Regulated Cell Proliferation and Angiogenesis in RMECs

Frontiers in Physiology, 2020
Background: Aberrant neovascularization resulting from inappropriate angiogenic signaling is closely related to many diseases, such as cancer, cardiovascular disease, and proliferative retinopathy.
Jun Ma, Jun Ma, Wenyi Tang, Ruiping Gu, Fangyuan Hu, Fangyuan Hu, Lei Zhang, Jihong Wu, Jihong Wu, Gezhi Xu, Gezhi Xu   +10 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Metabolic characterization of human aqueous humor in the cataract progression after pars plana vitrectomy

BMC Ophthalmology, 2018
Background While pars plana vitrectomy (PPV) has become the third most commonly performed surgery in the world, it can also induce multiple post complications easily.
Yinghong Ji, Xianfang Rong, Yi Lu
doaj   +1 more source

Heterogeneity of Axenfeld–Rieger Syndrome: Molecular and Clinical Findings in Chinese Patients

Frontiers in Genetics, 2021
Axenfeld–Rieger Syndrome (ARS) is a rare disease with a wide spectrum of ocular and systemic manifestations. The genetic spectrum of Chinese patients with ARS and genotype-phenotype correlations have yet to be described.
Youjia Zhang, Youjia Zhang, Xueli Chen, Li Wang, Xinghuai Sun, Xinghuai Sun, Xinghuai Sun, Yuhong Chen, Yuhong Chen   +8 more
doaj   +1 more source