Results 81 to 90 of about 4,186,077 (394)

An analysis of the impact of visual impairment on activities of daily living and vision-related quality of life in a visually impaired adult population

The British Journal of Visual Impairment, 2018
Previous research has shown that people with visual impairment are more likely to be malnourished and have reported to have difficulty shopping for, preparing, and eating food. They are also reported to have a poor quality of life. The present study aims
N. Jones, H. Bartlett, R. Cooke
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Pre-treatment With Ranibizumab Aggravates PDT Injury and Alleviates Inflammatory Response in Choroid-Retinal Endothelial Cells

Frontiers in Cell and Developmental Biology, 2020
Polypoidal choroidal vasculopathy (PCV) is the predominant subtype of exudative age-related macular degeneration in Asians. Although photodynamic therapy (PDT) is widely used for PCV treatment, its long-term beneficial effects are unsatisfactory ...
Yang Liu, Yang Liu, Min Zhu, Min Zhu, Ruowen Gong, Ruowen Gong, Xin Wang, Xin Wang, Lei Li, Lei Li, Gezhi Xu, Gezhi Xu   +11 more
doaj   +1 more source

The profiles and clinical significance of extraocular muscle-expressed lncRNAs and mRNAs in oculomotor nerve palsy

Frontiers in Molecular Neuroscience, 2023
IntroductionOculomotor nerve palsy (ONP) arises from primary abnormalities in the central neural pathways that control the extraocular muscles (EOMs).
Lianqun Wu, Lianqun Wu, Lianqun Wu, Mingsu Shi, Mingsu Shi, Mingsu Shi, Yu Liang, Yu Liang, Yu Liang, Jiaqiu Huang, Jiaqiu Huang, Jiaqiu Huang, Weiyi Xia, Weiyi Xia, Weiyi Xia, Hewei Bian, Hewei Bian, Hewei Bian, Qiao Zhuo, Qiao Zhuo, Qiao Zhuo, Chen Zhao, Chen Zhao, Chen Zhao   +23 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Prevelence and causes of visual impairment and blindness in older adults in an area of India with a high cataract surgical rate.

, 2010
BACKGROUND: The cataract surgical rate (CSR) in Gujarat, India is reported to be above 10,000 per million population. This study was conducted to investigate the prevalence and causes of vision impairment/blindness among older adults in a high CSR area ...
Ellwein, Leon B, John, Neena, Murthy, Gudlavalleti VS, Pokharel, Gopal, Vashist, Praveen   +4 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

SHP-2-Induced Activation of c-Myc Is Involved in PDGF-B-Regulated Cell Proliferation and Angiogenesis in RMECs

Frontiers in Physiology, 2020
Background: Aberrant neovascularization resulting from inappropriate angiogenic signaling is closely related to many diseases, such as cancer, cardiovascular disease, and proliferative retinopathy.
Jun Ma, Jun Ma, Wenyi Tang, Ruiping Gu, Fangyuan Hu, Fangyuan Hu, Lei Zhang, Jihong Wu, Jihong Wu, Gezhi Xu, Gezhi Xu   +10 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Comparing objective visual quality impairment detection in 2D and 3D video sequences [PDF]

, 2012
The skill level of teleoperator plays a key role in the telerobotic operation. However, plenty of experiments are required to evaluate the skill level in a conventional assessment.
Staelens, Nicolas, Boussaer, Arnaud, Vercammen, Nick, Van hoogenbemt, Geert, Vermeulen, Brecht, Demeester, Piet   +5 more
core   +2 more sources