Results 81 to 90 of about 384,676 (291)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Visually Impaired System

, 2020
{"references": ["Agarwal, R., Ladha, N., Agarwal, M., Majee, K. K., Das, A., Kumar, S., ... & Dey, R. (2017, October). Low cost ultrasonic smart glasses for blind. In 2017 8th IEEE Annual Information Technology, Electronics and Mobile Communication Conference (IEMCON) (pp. 210-213). IEEE..", "Balachandran, W., Cecelja, F., & Ptasinski, P. (2003,
Sourabh Zutti, Chetan Bulla, Sneha Potadar, Swati Kulkarni, Akshay Chavan   +4 more
openaire   +2 more sources

Prevelence and causes of visual impairment and blindness in older adults in an area of India with a high cataract surgical rate.

, 2010
BACKGROUND: The cataract surgical rate (CSR) in Gujarat, India is reported to be above 10,000 per million population. This study was conducted to investigate the prevalence and causes of vision impairment/blindness among older adults in a high CSR area ...
Ellwein, Leon B, John, Neena, Murthy, Gudlavalleti VS, Pokharel, Gopal, Vashist, Praveen   +4 more
core   +1 more source

Visual impairment and spectacle coverage rate in Baoshan district, China: population-based study [PDF]

, 2013
BACKGROUND: To investigate the prevalence and risk factors of visual impairment associated with refractive error and the unmet need for spectacles in a special suburban senior population in Baoshan District of Shanghai, one of several rural areas ...
Huijuan Zhao, Jianfeng Zhu, Meiling Liu, Mengjun Zhu, Rong Zhao, Xiangui He, Xiaowei Tong   +6 more
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Cerebral visual impairment

TNOA Journal of Ophthalmic Science and Research, 2018
In developing countries like India, cerebral visual impairment (CVI) is becoming common cause of visual impairment due to better neonatal care and advancement in technology. CVI is characterized by visual malfunction due to the retrochiasmal and visual association pathway pathology. The visual malfunction can present in any combination and any severity
Meenakshi Swaminathan, Yamini Patial
openaire   +3 more sources

Visual impairment and multimorbidity in a representative sample of the Spanish population  [PDF]

, 2015
BACKGROUND: In the context of population aging, visual impairment has emerged as a growing concern in public health. However, there is a need for further research into the relationship between visual impairment and chronic medical conditions in the ...
Ayuso Mateos, José Luis, Garin, Noe, Haro Abad, Josep Maria, Lara, Elvira, Miret, Marta, Moneta, Maria Victoria, Olaya Guzmán, Beatriz   +6 more
core   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

The Housing and Support Needs of Older People with Visual Impairment [PDF]

, 2002
Visual impairment is one of the most prevalent anddisabling conditions among older people, and yet verylittle research has been conducted that could inform thedevelopment of appropriate public services.
Hanson, J, Johnson, M, Percival, J, Zako, R   +3 more
core  

No-reference bitstream-based impairment detection for high efficiency video coding [PDF]

, 2012
Video distribution over error-prone Internet Protocol (IP) networks results in visual impairments on the received video streams. Objective impairment detection algorithms are crucial for maintaining a high Quality of Experience (QoE) as provided with ...
De Cock, Jan, Demeester, Piet, Janowski, Lucjan, Staelens, Nicolas, Van de Walle, Rik, Van Wallendael, Glenn   +5 more
core   +1 more source