Results 91 to 100 of about 924,003 (290)

What integrated working practices support or hinder effective referral pathways from health to education services for blind and partially sighted babies and young children? (Sharing our experience, Practitioner-led research 2008-2009; PLR0809/026) [PDF]

, 2009
Evidence indicates that young children and parents benefit from receiving specialist visual impairment (VI) education service support from an early stage following identification of a child’s sight condition. Early referral is key to this. Although there
Jennings, Julie
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Life in stop motion: a review of akinetopsia

Orphanet Journal of Rare Diseases
Akinetopsia is a rare visual cortical disorder in which patients lose the ability to perceive motion. Visual cortical disorders are often misdiagnosed by most clinicians because they misinterpret the cause of visual dysfunction.
Salma Mowafi, Rana Khashana, May Bakr
doaj   +1 more source

Visual Modeling Languages in Patient Pathways: Scoping Review

Interactive Journal of Medical Research
BackgroundPatient pathways (PPs) are presented as a panacea solution to enhance health system functions. It is a complex concept that needs to be described and communicated well.
Binyam Bogale, Märt Vesinurm, Paul Lillrank, Elisabeth Gulowsen Celius, Ragnhild Halvorsrud   +4 more
doaj   +1 more source

How Graphic Visual Health Warnings Affect Young Smokers\u27 Thoughts of Quitting [PDF]

, 2014
Two-thirds of adolescent and young adult smokers become lifetime smokers, and one-half of those lifetime smokers will die from this habit. The authors examine alternative persuasive pathways to thoughts of quitting taken by adolescent and young adult ...
Andrews, J. Craig, Burton, Scot, Kees, Jeremy, Netemeyer, Richard G   +3 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Parallel neural pathways in higher visual centers of the Drosophila brain that mediate wavelength-specific behavior

Frontiers in Neural Circuits, 2014
Compared with connections between the retinae and primary visual centers, relatively less is known in both mammals and insects about the functional segregation of neural pathways connecting primary and higher centers of the visual processing cascade ...
Hideo eOtsuna, Kazunori eShinomiya, Kei eIto   +2 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A multi-pathway hypothesis for human visual fear signaling

Frontiers in Systems Neuroscience, 2015
A hypothesis is proposed for five visual fear signaling pathways in humans, based on an analysis of anatomical connectivity from primate studies and human functional connectivity from brain imaging studies.
David N Silverstein, David N Silverstein, Martin eIngvar, Martin eIngvar   +3 more
doaj   +1 more source