Results 81 to 90 of about 3,371,601 (332)
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Multi-cultural visualization : how functional programming can enrich visualization (and vice versa) [PDF]
, 2006 The past two decades have seen visualization flourish as a research field in its own right, with advances on the computational challenges of faster algorithms, new techniques for datasets too large for in-core processing, and advances in understanding ...
Borgo, Rita +3 more
core
A Systematic Review of Visualization Techniques and Analysis Tools for Eye-Tracking in 3D Environments [PDF]
, 2022 Veronica Sundstedt, Valeria Garro
openalex +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
7 Dimensions of software change patterns
Scientific ReportsEvolving software is a highly complex and creative problem in which a number of different strategies are used to solve the tasks at hand. These strategies and reoccurring coding patterns can offer insights into the process.
Mario Janke, Patrick Mäder
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Task-Based Effectiveness of Basic Visualizations
, 2018 Visualizations of tabular data are widely used; understanding their effectiveness in different task and data contexts is fundamental to scaling their impact. However, little is known about how basic tabular data visualizations perform across varying data
Demiralp, Cagatay +2 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
A Machine Learning-Based Pipeline for the Extraction of Insights from Customer Reviews
Big Data and Cognitive ComputingThe efficiency of natural language processing has improved dramatically with the advent of machine learning models, particularly neural network-based solutions. However, some tasks are still challenging, especially when considering specific domains. This
Róbert Lakatos +7 more
doaj +1 more source
Fully automatic wound segmentation with deep convolutional neural networks
Scientific Reports, 2020 Acute and chronic wounds have varying etiologies and are an economic burden to healthcare systems around the world. The advanced wound care market is expected to exceed $22 billion by 2024.
Chuanbo Wang +7 more
doaj +1 more source