Results 41 to 50 of about 1,769,658 (332)

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Comparison of Respiratory Functions of Athletes Engaged in Different Sports Branches

Türk Spor ve Egzersiz Dergisi, 2014
The purpose of this study was to research pulmonary functions of sedentary males and athletes in different team sports branches in the same age group. This study was conducted on male athletes in15-16 age group who participate in matches with license in ...
Mehmet Çebi, Pelin Akyol, Tülin Atan
doaj  

STUDY OF RESULTS BETWEEN INITIAL AND FINAL SPECIFIC TESTS IN WOMEN WITH NORMAL PREGNANCY [PDF]

Trakia Journal of Sciences, 2019
PURPOSE: The aim of this study was to achieve a control model of basic functional indicators established by comparative analysis between the results of initial and final anthropometric and functional tests in women with normal pregnancy.
Ir. Nesheva
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Genome-wide association analysis identifies six new loci associated with forced vital capacity [PDF]

, 2014
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies and ...
A Bill Musk, A Hofman, A Rosendahl, A Sountoulidis, Adaikalavan Ramasamy, Akshay Sood, AL Dixon, Alan F Wright, Alan L James, Alanna C Morrison, Albert Hofman, Albert Vernon Smith, Alexander Teumer, Alexessander Couto Alves, Alicja R Rudnicka, Ana Viñuela, Andrew P Morris, André G Uitterlinden, Ani Manichaikul, Anne Newman, Anne Viljanen, Anneli Pouta, AP Boyle, AS Dimas, AT Kho, B Devlin, B Gombojav, B Servin, Beate Koch, Bharat Thyagarajan, BL Browning, Blair H Smith, Bonnie R Joubert, Bruce M Psaty, Bruno H Stricker, Caroline Hayward, CE Elks, Chris Oldmeadow, Christian Gieger, Christopher J Hammond, Cisca Wijmenga, CJ Willer, CJ Zappala, Claudia Flexeder, CM Lindgren, CS Carlson, Daan W Loth, Dana B Hancock, David Couper, David J Lederer, David J Porteous, David P Strachan, DB Hancock, DB Hancock, Deborah L Jarvis, Dirkje S Postma, DJ Gottlieb, DR Nyholt, E Hodge, E Melén, E Repapi, EE Eichler, Elizabeth G Holliday, Erik Ingelsson, Erik Melén, Ernst Omenaas, Esteban G Burchard, Eva Albrecht, F Ashley, Fernando Rivadeneira, Fien M Verhamme, G Lettre, G Raghu, Gail Davies, Generation Scotland, George T O'Connor, Gudny Eiriksdottir, Guo Li, Guy G Brusselle, H Lango Allen, H Marike Boezen, H Takizawa, Harald Grallert, Harry Campbell, Henry Völzke, HJ Westra, HM Lee, Holger Schulz, Holly Trochet, Ian J Deary, Ian P Hall, Ian Sayers, Ida Surakka, Igor Rudan, Isabelle Pin, Ivana Kolcic, J Li, J Marchini, J Sung, J Sung, J Yang, Jaakko Kaprio, James F Wilson, JB Wilk, JB Wilk, Jemma B Wilk, Jennie Hui, Jennifer E Huffman, Jerome I Rotter, JH Park, Jing Hua Zhao, JM Cheverud, Joachim Heinrich, John Beilby, John M Starr, John R Attia, Joohon Sung, Josée Dupuis, Joyce B J van Meurs, JR Gibbs, Judith M Vonk, Juha Pekkanen, K Musunuru, K Zhang, Kari E North, Ken R Bracke, Kim de Jong, Kirsi H Pietiläinen, Kristin M Burkart, Kurt Lohman, Lars Lind, Laura R Loehr, Lenore J Launer, Leslie A Lange, Lewis J Smith, Lies Lahousse, Lina Zgaga, LJ Palmer, Lorna M Lopez, Louise V Wain, M Kimura, M Soler Artigas, M Uhlen, Marcy F Petrini, Marjo-Riitta Jarvelin, Marjolein J Peters, Markku Heliövaara, Martin D Tobin, Mary Wojczynski, María Soler Artigas, Matthias Wjst, Melissa Garcia, Mi Kyeong Lee, Mika Kähönen, Myriam Fornage, N van Putte-Katier, Nadia Hansel, Nathan C Gaddis, Nicholas D Hastie, Nicholas J Wareham, Nora Franceschini, O Dale Williams, Ozren Polasek, P Lange, Patricia A Cassano, Pau Navarro, Peter K Joshi, PG Burney, Pieter S Hiemstra, Pirro G Hysi, PJ McLaughlin, Qing Duan, R Graham Barr, Rajesh Kumar, Regina Hampel, Robert A Scott, Rodney J Scott, Ryan L Minster, Samuli Ripatti, Sarah H Wild, Sina A Gharib, SR Browning, ST Weiss, Stefan Enroth, Stefan Karrasch, Stephanie J London, Stephen B Kritchevsky, Stephen S Rich, Susan Campbell, Susan R Heckbert, Susan Redline, Sven Gläser, Taina Rantanen, Tamara B Harris, Tatijana Zemunik, Tess D Pottinger, Thomas Lumley, Thor Aspelund, Timothy D Spector, Tove Fall, Ulf Gyllensten, Veronique Vitart, Vilmundur Gudnason, WB Kannel, Wei Gao, Wenbo Tang, Wendy B White, Wendy L McArdle, WI de Boer, Woo Jin Kim, Xiangjun Gu, Xin-Qun Wang, Y Li, Yeon-Mok Oh, Yongmei Liu, YS Cho, Åsa Johansson   +216 more
core   +4 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Perbedaan Nilai Vital Capacity, Forced Vital Capacity Dan Forced Expiratory Volume in One Second Antar Cabang Olahraga Pada Atlet Usia 6-12 Tahun [PDF]

, 2015
Background: Physical activity during childhood and adolescence has an important impact on health and life quality. The earlier study shown that regular exercise has significant impact to the lung and cardiovascular function.
Kumaidah, E. (Endang), Mubarok, W. (Wildan), Supatmo, Y. (Yuswo)   +2 more
core  

A formulation of the relaxation phenomenon for lane changing dynamics in an arbitrary car following model

, 2020
Lane changing dynamics are an important part of traffic microsimulation and are vital for modeling weaving sections and merge bottlenecks. However, there is often much more emphasis placed on car following and gap acceptance models, whereas lane changing
Gao, H. Oliver, Keane, Ronan
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Wildlife reintroduction: considerations of habitat quality at the release site. [PDF]

, 2006
BACKGROUND: Assessing the suitability of a habitat prior to the release of animals is vital. Proper assessment of the flora will allow reintroduction programmes to determine whether the area will be capable of supporting the released animals in the long ...

core   +1 more source