Results 21 to 30 of about 4,117 (224)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Servicios públicos domiciliarios: ¿derechos humanos o productos para la venta? caso Medellín (home utilities: are they human rights or products for sale? the medellin case)

open access: yesEl Ágora USB, 2014
RESUMEN: El presente artículo presenta los resultado de investigación encaminada a demostrar y visibilizar, en la ciudad de Medellín, las múltiples afectaciones a personas por la ausencia de servicios públicos domiciliarios en sus viviendas, aún y la ...
Fabián Alirio Mazo Elorza
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Propiedades psicométricas del Cuestionario de Sucesos Vitales (CSV) en una muestra de adultos ecuatorianos

open access: yesActualidades en Psicología
Objetivo. El objetivo del estudio fue adaptar y validar el Cuestionario de Sucesos Vitales (CSV) en el contexto ecuatoriano. Método. El diseño del estudio fue de tipo instrumental y participaron 417 personas adultas (M = 37.1; DE = 8.67). Resultados.
Jimena B. Agila-Cuji   +1 more
doaj   +1 more source

Conocimientos y actitudes de los profesionales sanitarios en el proceso de declaración de las voluntades vitales anticipadas

open access: yesAtención Primaria, 2015
Objetivo: Identificar áreas de interés subyacentes en el proceso de Declaración de Voluntades Vitales Anticipadas (DVVA) y consensuar un cuestionario de conocimientos y actitudes dirigido a profesionales de la salud.
Eugenio Contreras-Fernández   +3 more
doaj   +1 more source

Enrique García Santo-Tomás, "Signos vitales. Procreación e imagen en la narrativa áurea"

open access: yesStudia Aurea: Revista de Literatura Española y Teoría Literaria del Renacimiento y Siglo de Oro, 2021
Reseña de Enrique García Santo-Tomás, Signos vitales. Procreación e imagen en la narrativa áurea.
Jorge García
doaj   +1 more source

Measuring Vitality [PDF]

open access: yesJournal of the Royal Society of Medicine, 1990
Subjective perceptions of mental and physical energy were measured by the use of visual analogue scales (VAS) over the course of a week in a group of normal volunteers. These variables were found to correlate, highly both with one another and with assessments of vigour and fatigue measured with a standard adjectival format.
C, Wood, M E, Magnello, T, Jewell
openaire   +2 more sources

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