Results 51 to 60 of about 1,255,589 (356)

Testamentos vitales. [PDF]

open access: yes, 2007
El Testamento vital, término convencional que recogemos pese a no ser aceptado en la legislación española, aspira a mantener la ilusión de control autónomo sobre la gestión de la enfermedad.
Serrano, J.M. (José Miguel)
core  

Ocurrencia, grado de afectación y controlabilidad de los eventos vitales en el desarrollo de la psicopatología: ¿impacto ambiental o consecuencia de una personalidad vulnerable? [PDF]

open access: yes, 2017
II Jornades d’Investigació per a l’estudiantat de la Facultat de Ciències de la SalutIntroducción: La personalidad y los eventos vitales influyen en el desarrollo de psicopa- tología. No obstante, es posible que la afectación y ocurrencia de los eventos
Cuevas Carda, Andrea   +2 more
core   +1 more source

Resiliencia en adolescentes expuestos a condiciones vitales de riesgo

open access: yes, 2017
Antecedentes: La resiliencia se ha convertido en un tema central en el estudio y en la intervencion con adolescentes. Las investigaciones realizadas sobre dicho tema encuentran grandes diferencias en su capacidad de afrontar el estres y la adversidad. El
A. Castillo   +2 more
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

La razón y sus horizontes vitales en la fenomenología de Edmund Husserl [PDF]

open access: yes, 2013
Husserl rejects the contrast between human life as an irrational factum and reason as an objectifying force that is hostile to life. Hence he moves away from the incompatibility between philosophy as science and philosophy of life.
Walton, Roberto Juan
core  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Cuestionario de Sucesos Vitales (CSV): Estructura factorial, características psicométricas y datos normativos

open access: yes, 2017
: Life Events Questionnaire (CSV): Factor structure, psychometric properties and normative data. The aim of the present study was to validate the Life Events Questionnaire (CSV). Two large and independent samples were used (age range 19 to 67 years).
B. Sandín, Paloma Chorot
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Monitor de constantes vitales para animales de laboratorio [PDF]

open access: yes, 2019
Las constantes vitales son parámetros que hay que tener en cuenta para conocer el diagnóstico clínico de personas y animales. Algunas de las constantes vitales más importantes son la frecuencia cardíaca, el nivel de oxigenación en la sangre, la ...
González Cárdenas, Alberto
core  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

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