Results 51 to 60 of about 60,694 (274)
Persona y Derecho, 1970 El Testamento vital, término convencional que recogemos pese a no ser aceptado en la legislación española, aspira a mantener la ilusión de control autónomo sobre la gestión de la enfermedad. A su vez, el testamento vital eutanásico aparece como el argumento que permitiría vincular autonomía con aceptación del homicidio eutanásico.
Serrano, J.M. (José Miguel) +1 more
openaire +3 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Objetivos vitales en jóvenes y en adultos mayores sanos y con enfermedades crónicas
Pensamiento Psicológico, 2015 Objetivo. Este estudio pretende explorar los objetivos vitales en diferentes momentos de la vida y determinar la influencia de la edad y el estado de salud en ellos. Método.
Feliciano Villar, María del Carmen Zea
doaj
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Una aproximación a la medición del subregistro de nacimientos en las estadísticas vitales de México
Estudios Demográficos y Urbanos, 2005 En este trabajo se analiza el subregistro de nacimientos en las estadísticas vitales de México a la luz de la información del xii Censo de Población y Vivienda del año 2000, el cual incluyó por primera vez información relativa a la fecha de nacimiento ...
Alfonso S. González Cervera +1 more
doaj
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Modelos de desarrollo, identidad masculina y familia: dos generaciones de trabajadores de Huachipato
Punto Género, 2016 La “Compañía de Acero del Pacífico” (CAP) es considerada, y en específico a la planta siderúrgica Huachipato, como un eje industrializador relevante en la región del Biobío. Este estudio aborda las trayectorias vitales de trabajadores varones de la misma,
Inti Fernando Fuica Rebolledo
doaj +1 more source