Results 81 to 90 of about 11,774 (289)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

La conception ternaire corps/esprit/âme dans la pensée médicale au cours des âges

Cahiers d'Études du Religieux- Recherches Interdisciplinaires, 2013
The progressive emergence of a rational medical knowledge did not prevent links with philosophy (mainly Plato and Aristotle) and theology. The tripartition body/soul/spirit (the meaning of these terms varying according to the different periods) is one of
Thierry Lavabre-Bertrand
doaj   +1 more source

Mechanical Neuroscience: Emil du Bois-Reymond’s Innovations in Theory and Practice [PDF]

, 2015
Summary of the major innovations of Emil du Bois-Reymond (1818 ...
Finkelstein, Gabriel
core   +3 more sources

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

De la palabra al género: un itinerario

Filología, 2014
La obra de Ana María Barrenechea se caracteriza por una atención a los modos de leer. Aquí se propone, más allá de las adhesiones disciplinares y a partir de unas determinadas experiencias de trabajo (es decir: de vida comunitaria) una relectura de la ...
Daniel Link
doaj  

Comparison of veterinary drugs and veterinary homeopathy: part 1 [PDF]

, 2017
For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of ...
AABEL, AHN, ANICK, BEKELMAN, BELL, BELL, BELL, BELLAVITE, BELON, BELON, BOERICKE, CALABRESE, CALABRESE, CALABRESE, CALABRESE, CAMPBELL, CANFIELD, CARTWRIGHT, CHAMBERS, CHAMBERS, CHAN, CHAPMAN, CHIKRAMANE, CONZEMIUS, COWAN, CROSKERRY, CROSKERRY, CUCHERAT, CUNNINGHAM, DAVENAS, DI GIROLAMO, DOEHRING, DOUST, EASTERBROOK, ELIA, ENNIS, ERNST, FLOWER, FRASER, GARTLEHNER, GAY, GODWIN, GOLDACRE, GREGORY, GREGORY, GREGORY, GRIMES, GRUEN, GRUEN, HAHNEMANN, HARTMAN, HEKTOEN, HEKTOEN, HIRST, HOVI, HRÓBJARTSSON, IOANNIDIS, IOANNIDIS, IOANNIDIS, IOANNIDIS, IOANNIDIS, JACOBS, JADAD, JONAS, JONAS, KAHANB, KAHNEMAN, KAYNE, KAYNE, KOHN, LEE, LEES, LEES, LEES, LEXCHIN, LILLEY, LINDE, MADDOX, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATHIE, MATUTE, MCGAURAN, MCKENZIE, MILAZZO, MILGROM, MONTAGNIER, NICOLAI, OWEN, OWEN, OWEN, OWEN, OXTOBY, PAULSON, PINTO, PRASAD, RAO, REILLY, REY, REY, RILEY, ROY, RUDOLF, SACKETT, SAPOSNIK, SARGEANT, SARGEANT, SCHULZ, SHANG, SHAW, SHERR, SHOJANIA, SMITH, SMITH, STERN, TEMGIRE, TOUTAIN, VAN WIJK, VANDENBERG, VIERA, WHITEHEAD, WHITING, WORLD HEALTH, ZOONOSES AND PUBLIC   +128 more
core   +5 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Do psíquico ao somático: notas sobre a reconfiguração do self contemporâneo

História, Ciências, Saúde: Manguinhos
Resumo O artigo examina a passagem de uma compreensão psicológica da pessoa para uma compreensão somática/cerebral. A discussão centra-se na dualidade que marca a cultura ocidental moderna, entre a visão iluminista e racionalista do mundo e a visão ...
Jane Russo
doaj   +1 more source

ADDITIONAL REMARKS ON BÁSNIK A ŽENA/THE POET AND THE WOMAN (TWO VERSIONS OF THE SAME POEM) [PDF]

Slovenska Literatura, 2010
The aim of the article is to show the process of transformation of Smrek´s poetic gesture according to how the differences between the versions of poetic composition Básnik a žena (The Poet and the Woman) published in the magazine (1925) and in the book (
Michal Habaj
doaj