Results 41 to 50 of about 510,546 (297)

Telomerase in Brain: The New Kid on the Block and Its Role in Neurodegenerative Diseases

Biomedicines, 2021
Telomerase is an enzyme that in its canonical function extends and maintains telomeres, the ends of chromosomes. This reverse transcriptase function is mainly important for dividing cells that shorten their telomeres continuously.
Gabriele Saretzki, Tengfei Wan
doaj   +1 more source

Study on the Classification Method of Urban Vitality Spatial Pattern Based on Full-Time Vitality Spectrum:A Case Study of Tianjin, China [PDF]

, 2020
Urban vitality represents the use of urban space. The higher the vitality, the stronger the attraction. How urban space is used in the planning process and how the vitality changes within the space during the day are important evaluation
Gao, Ziwei, Sun, Zongyao, Zeng, Peng
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Liaison Old Age Psychiatry Service in a Medical Setting: Description of the Newcastle Clinical Service

Nursing Research and Practice, 2011
Liaison Old Age Psychiatry services (LOAP) have begun to emerge in the UK and further development of the service is supported by the latest health policies.
E. B. Mukaetova-Ladinska, G. Cosker, M. Coppock, M. Henderson, Y. Ali Ashgar, A. Hill, A. Scully, D. Robinson, K. Sells, S. Brotherton, C. Lowthian   +10 more
doaj   +1 more source

End-of-life care in the Dutch medical curricula

Perspectives on Medical Education, 2018
Introduction Future doctors must be trained in giving appropriate care to terminal patients. In several countries, medical curricula have been reviewed for the attention devoted to end-of-life care (ELC).
Josefien de Bruin, Mary-Joanne Verhoef, Joris P. J. Slaets, David van Bodegom   +3 more
doaj   +1 more source

Preparing undergraduate students for clinical work in a complex environment: evaluation of an e-learning module on physiotherapy in the intensive care unit

BMC Medical Education, 2020
Background Intensive Care Units (ICUs) are daunting environments for physiotherapy (PT) students performing clinical rotations. To prepare students for this environment, a newly developed, evidence-based e-learning module was designed and implemented in ...
Mel E. Major, Stephan P. J. Ramaekers, Raoul H. H. Engelbert, Marike Van der Schaaf   +3 more
doaj   +1 more source

The effects of the COVID-19 lockdowns on motor skill development of 6- and 7-year old children in the Netherlands: a longitudinal study

BMC Public Health, 2023
Background The closing of schools and sports clubs during the COVID-19 lockdown raised questions about the possible impact on children’s motor skill development.
Anne R. den Uil, Hemke van Doorn, Mandy Schweitzer, Mirka Janssen, Ron H. J. Scholte, Vincent Busch   +5 more
doaj   +1 more source

Achieving and Maintaining Cognitive Vitality With Aging [PDF]

, 2001
This report contains the summary results of a workshop held at Canyon Ranch Health Resort in Tucson, Arizona. Physicians and scientists shed light on the process of cognitive aging.
Howard Fillit, Robert N. Butler
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Escape, expand, embrace: the transformational lived experience of rediscovering the self and the other while dancing with Parkinson’s or Multiple Sclerosis

International Journal of Qualitative Studies on Health & Well-Being, 2023
Purpose The purpose of this study was to explore the lived experience of dancing with Parkinson’s and Multiple Sclerosis in an inclusive dance group called ReDiscoverMe (RDM).
Anna M. Carapellotti, Hannie (J.E.M.) Meijerink, Christine Gravemaker-Scott, Lucia Thielman, Renée Kool, Natalie Lewin, Tineke A. Abma   +6 more
doaj   +1 more source