Results 81 to 90 of about 521,031 (345)

Comprehensive measurement of stroke gait characteristics with a single accelerometer in the laboratory and community: a feasibility, validity and reliability study

Journal of NeuroEngineering and Rehabilitation, 2017
Background Application of objective measurement of stroke gait with accelerometer-based wearable technology and associated algorithms is increasing, despite reports questioning the accuracy of this technique in quantifying specific stroke-related gait ...
Sarah A. Moore, Aodhan Hickey, Sue Lord, Silvia Del Din, Alan Godfrey, Lynn Rochester   +5 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Teacher Vital Signs: A Two-Country Study of Teacher Vitality

, 2010
Defining teacher vitality as the vigor, energy, passion, and joy teachers bring to their classroom, students and colleagues; this article describes an international, comparative, qualitative, phenomenological study of teachers’ lived experiences to ...
Cavner, Delta, Ed.D.
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What is Probable Cause, and Why Should We Care?: The Costs, Benefits, and Meaning of Individualized Suspicion [PDF]

, 2010
Taslitz defines probable cause as having four components: one quantitative, one qualitative, one temporal, and one moral. He focuses on the last of these components.
Taslitz, Andrew E.
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer’s disease and experimental chronic cerebral hypoperfusion

Acta Neuropathologica Communications
Neurovascular unit mural cells called ‘pericytes’ maintain the blood-brain barrier and local cerebral blood flow. Pathological changes in the hippocampus predispose to cognitive impairment and dementia.
Yoshiki Hase, Dan Jobson, Jeremy Cheong, Kelvin Gotama, Luciana Maffei, Mai Hase, Alhafidz Hamdan, Ren Ding, Tuomo Polivkoski, Karen Horsburgh, Raj N. Kalaria   +10 more
doaj   +1 more source

How nursing students’ placement preferences and perceptions of community care develop in a more ‘community-oriented’ curriculum: a longitudinal cohort study

BMC Nursing, 2020
Background Extramuralisation in healthcare has influenced medical and nursing curricula internationally with the incorporation of themes related to primary/ community care. Despite this, students do not easily change their career preferences.
Margriet van Iersel, Corine H. M. Latour, Marjon van Rijn, Rien de Vos, Paul A. Kirschner, Wilma J. M. Scholte op Reimer   +5 more
doaj   +1 more source

Project vital: Community revitalization industry report [PDF]

, 2018
ViTAL (Vitality Through Active Living) FIJIAN PROJECT The ViTAL project aims to aid in the reduction of non-communicable diseases (NCDs) through investment in the health and well-being of women by increasing the level of participation in physical ...
Longhurst, Glynis
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Measuring cultural vitality in communities [PDF]

Until recently, arts and culture data collected as part of urban revitalization planning focused on large institutions. The Urban Institute’s Arts and Culture Indicators Project provides a richer understanding of communities’ cultural strength and how it
Maria Rosario Jackson
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