This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar+4 more
wiley +1 more source
100 Years of Vitamins: The Science of Formulation is the Key to Functionality
Micronutrients and nutraceuticals such as vitamins, carotenoids, polyunsaturated fatty acids and polyphenols are classes of food ingredients that are essential for human health and well-being.
Alexandra Teleki+2 more
doaj +1 more source
Calculation of the Sun exposure time for the synthesis of vitamin D in Urcuquí, Ecuador [PDF]
The synthesis of vitamin D is strongly linked to the availability of solar energy. For a long time, it was clear that using the erythemal irradiances is a good choice to calculate the exposure time. Several authors argue that this method of minimum exposure time overestimates the calculation of the solar irradiance of vitamin D.
arxiv
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie+5 more
wiley +1 more source
Micronutrient Intakes and Status in the Protein Transition: A Systematic Review
A food systems transformation is required to improve both human and planetary health. A reduction in the consumption of high-impact animal-based foods will be necessary, especially in high-income settings. Ensuring nutritional adequacy in this transition
Ursula M. Leonard+3 more
doaj +1 more source
Electronic structure and correlations of vitamin B12 studied within the Haldane-Anderson impurity model [PDF]
We study the electronic structure and correlations of vitamin B12 (cyanocobalamine) by using the framework of the multi-orbital single-impurity Haldane-Anderson model of a transition-metal impurity in a semiconductor host. The parameters of the effective Haldane-Anderson model are obtained within the Hartree-Fock (HF) approximation.
arxiv +1 more source
An investigation of vitamin D metabolism in kiwi (Apteryx mantelli), tuatara (Sphenodon punctatus) and New Zealand sea lion (Phocarctos hookeri) and the relationship of vitamin D metabolism with their life history characteristics : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Studies at Massey University, Turitea, Palmerston North, New Zealand [PDF]
Vitamin D, a fat-soluble vitamin, has a wide range of functions in vertebrates. The aim of the study was to determine if the evolutionary history of different animal species affects their predominant route of vitamin D metabolism.
Kale, Madhumita Sanjay
core
Low 25-OH vitamin D levels at time of diagnosis and recurrence of ovarian cancer. [PDF]
The objective of this study was to evaluate the correlation between 25-OH vitamin D and ovarian cancer as a diagnostic marker or recurrence disease marker.
Anastasi, Emanuela+6 more
core +1 more source
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba+8 more
wiley +1 more source
Background Consumption of diets from sustainable sources is required for planetary health, however, large sections of the population, including females of reproductive age and children, will be at risk of not meeting their micronutrient (MN) requirements
Ursula M. Leonard, Mairead E. Kiely
doaj +1 more source