Results 51 to 60 of about 1,458,636 (316)

Non-skeletal activities of vitamin d: From physiology to brain pathology [PDF]

, 2019
Vitamin D is a secosteroid hormone regulating the expression of almost 900 genes, and it is involved in the regulation of calcium and phosphate metabolism, immune response, and brain development.
Bruna Lo Sasso, Chiara Bellia, Concetta Scazzone, Giorgia Iacolino, Giulia Bivona, Luisa Agnello, Marcello Ciaccio   +6 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Vitamin Regulation of Osteoclast Differentiation

Central Asian Journal of Medical Sciences, 2020
Objectives: Vitamins play critical roles in cellular metabolism, growth, and many enzymatic processes of the human body. They are also crucial in signal transduction and transcription pathways of many processes, including osteoclast differentiation. This
Erdenezaya Odkhuu, Shijir Narmandakh, Munkhjargal Zinamyadar, Juramt Bold, Avirmed Amgalanbaatar, Enebish Sundui   +5 more
doaj   +1 more source

Impaired release of Vitamin D in dysfunctional adipose tissue: New cues on Vitamin D supplementation in obesity [PDF]

, 2017
Context: Vitamin D accumulates in adipose tissue (AT) and vitamin D deficiency is frequent in obesity. Objective: We hypothesize that trafficking of vitamin D is altered in dysfunctional AT.
Azzena, Bruno, DE FILIPPIS, Vincenzo, DE TONI, Luca, DI NISIO, Andrea, Foresta, Carlo, Opocher, Giuseppe, Plebani, Mario, Rocca, MARIA SANTA, Sabovic, Iva, Vettor, Roberto   +9 more
core   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Analysis of Volatile Aroma Components in Different Parts of Shiitake Mushroom (Lentinus edodes) Treated with Ultraviolet C Light-Emitting Diodes Based on Gas Chromatography–Ion Mobility Spectroscopy

Molecules
Further assessment of ultraviolet C light-emitting diode (UVC-LED) irradiation for influencing shiitake mushrooms’ (Lentinus edodes) volatile and sensory properties is needed.
Daihua Hu, Yulin Wang, Fanshu Kong, Danni Wang, Chingyuan Hu, Xu Yang, Xiaohua Chen, Wang Chen, Zili Feng   +8 more
doaj   +1 more source

Association between vitamin d deficiencies in sarcoidosis with disease activity, course of disease and stages of lung involvements [PDF]

, 2017
Background: Despite negative association between 25-hydroxy vitamin D and incidence of many chronic respiratory diseases, this feature was not well studied in sarcoidosis. Current study investigated the association between 25-hydroxy vitamin D deficiency
Abedini, A, Adcock, IM, Kazempour-Dizaji, M, Kiani, A, Mirenayat, MS, Mortaz, E, Taghavi, K   +6 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Alloferon and IL-22 receptor expression regulation on the pathogenesis of imiquimod-induced psoriasis

Scientific Reports
Psoriasis is an immune-mediated inflammatory skin disease. IL-22, a proinflammatory cytokine, is implicated in psoriasis pathogenesis; however, there is currently no established biological treatment targeting IL-22 or its receptor, IL-22Rα.
Tomoyo Agura, Hyejung Jo, Seulgi Shin, Yoojin Jang, Chong Won Choi, In Su Gwak, Jae Seung Kang, Yejin Kim   +7 more
doaj   +1 more source

NUTRITIONAL RICKETS – REVISITED

Медицинский совет, 2016
Nutritional rickets is a bone disease in early childhood resulting in bone pain, delayed motor development, and bending of the bones, caused by vitamin D deficiency and/or inadequate dietary calcium intake. The consequences of nutritional rickets include
P. Pludowski, I. N. Zakharova
doaj   +1 more source