Results 61 to 70 of about 371,861 (249)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

A lipid-soluble antioxidant from polyallomer centrifuge tubes

open access: yesJournal of Lipid Research, 1974
Santowhite, a commercial antioxidant used in the manufacture of polypropylene, contaminates 12-ml polyallomer tubes to the extent of 0.2–0.3 mg/tube. It is distributed through the plastic and appears as a microscopic dust on the tubes' surfaces.
Clyde E. Opliger   +2 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Stability of Vitamins and Minerals in Coated and Extruded Fortified Rice Kernels Stored under Real-Life Conditions over Two Years and Implications for Standards

open access: yesRice Science
Rice fortification is a cost-effective intervention to address and prevent micronutrient deficiencies in contexts where rice is a staple food. The stability of such added micronutrients is of critical importance, especially when rice is stored under ...
Werner NADER   +7 more
doaj   +1 more source

Vitamin D: The "sunshine" vitamin.

open access: yesJournal of pharmacology & pharmacotherapeutics, 2012
Vitamin D insufficiency affects almost 50% of the population worldwide. An estimated 1 billion people worldwide, across all ethnicities and age groups, have a vitamin D deficiency (VDD). This pandemic of hypovitaminosis D can mainly be attributed to lifestyle (for example, reduced outdoor activities) and environmental (for example, air pollution ...
Nair, Rathish, Maseeh, Arun
openaire   +2 more sources

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development [PDF]

open access: yes, 2013
Background: Vitamin D insufficiency has been associated with the occurrence of various types of cancer, but causal relationships remain elusive. We therefore aimed to determine the relationship between genetic determinants of vitamin D serum levels and ...
Jörg Bojunga   +127 more
core   +3 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Recent Advances in the Synthesis of K-Vitamins

open access: yesCHIMIA, 1986
The term «Vitamin K» is a collective name and embraces a whole series of 2-methyl-1,4- naphthoquinone derivatives which play a decisive part in the control of blood clotting.
August Rüttimann
doaj   +1 more source

Vitamin D – The Vitamin Hormone

open access: yesSouth African Family Practice, 2016
Vitamin D is a fat-soluble vitamin that plays an important role in bone metabolism and seems to have some anti-inflammatory and immune-modulating properties. For most people sunlight is the most important source of vitamin D. The time required to make sufficient vitamin D varies according to a number of environmental, physical and personal factors, but
openaire   +3 more sources

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