Results 81 to 90 of about 2,020,358 (433)

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Nutritional Status and Symptoms in Preschool Children With Autism Spectrum Disorder: A Two-Center Comparative Study in Chongqing and Hainan Province, China

Frontiers in Pediatrics, 2020
Objective: The study aimed to compare the nutritional status and symptoms of preschool children with autism spectrum disorder (ASD) from two regions of China, and to analyze the association between nutritional status and symptoms of ASD.Methods: In this ...
Jiang Zhu, Jiang Zhu, Min Guo, Min Guo, Ting Yang, Ting Yang, Xi Lai, Xi Lai, Ting Tang, Ting Tang, Jie Chen, Jie Chen, Ling Li, Tingyu Li, Tingyu Li   +14 more
doaj   +1 more source

Influence of dietary vitamin E supplementation on cholesterol oxidation and fresh colour in beef aged for 3 and 14 days [PDF]

, 2016
The effects of dietary vitamin E supplementation on the susceptibility to lipid oxidation and colour of the Longissimus thoracis (LT) muscle aged in vacuum packaged conditions for 3 or 14 days were studied.
Bruno Ronchi, Emanuela Filippb, Federico Vincenti, Francesca Perer, GIUSTI, Anna Maria, MACONE, ALBERTO, Miriam Iacurto, Pier Paolo Danieli   +7 more
core   +1 more source

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Experimental data suggest that intravenous vitamin C may attenuate inflammation and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS). Objective To determine the effect of intravenous vitamin C infusion on
A. Fowler, J. Truwit, R. D. Hite, P. E. Morris, C. DeWilde, Anna Priday, B. Fisher, L. Thacker, R. Natarajan, D. Brophy, R. Sculthorpe, R. Nanchal, A. Syed, J. Sturgill, G. Martin, J. Sevransky, M. Kashiouris, Stella M. Hamman, K. Egan, A. Hastings, Wendy Spencer, Shawnda Tench, Omar Mehkri, James Bindas, A. Duggal, Jeanette Graf, Stephanie Zellner, L. Yanny, Catherine McPolin, Tonya Hollrith, D. Kramer, Charles I. Ojielo, T. Damm, Evan P. Cassity, Aleksandra Wieliczko, M. Halquist   +35 more
semanticscholar   +1 more source

Bone‐wise rigid registration of femur, tibia, and fibula for the tracking of temporal changes

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Multiple myeloma (MM) induces temporal alterations in bone structure, such as osteolytic bone lesions, which are challenging to identify through manual image interpretation. The large variation in radiologists' assessments, even at expert centers, further complicates diagnosis.
Arttu Ruohola, Ville Haapamäki, Eero Salli, Tuomas Kaseva, Marko Kangasniemi, Sauli Savolainen   +5 more
wiley   +1 more source

Vitamins, supplements and COVID-19: a review of currently available evidence

Drugs in Context, 2021
Background: In the midst of the COVID-19 pandemic, there has been an information overload of health data (both accurate and inaccurate) available to the public.
Lauren Speakman, Sarah Michienzi, Melissa Badowski   +2 more
doaj   +1 more source

Comparative analysis of vitamin D content in sardines canned in olive oil and water [PDF]

, 2016
Vitamin D is a fat-soluble hormone primarily responsible in maintaining plasma calcium and phosphorus homeostasis in humans. Vitamin D insufficiency and deficiency is a global health issue.
Kalajian, Tyler Arek
core   +1 more source

Plasma kinetics of vitamin A in humans after a single oral dose of [8,9,19-13C]retinyl palmitate

Journal of Lipid Research, 1996
The kinetics of vitamin A and its major metabolites were investigated in humans. Eleven healthy male subjects ingested 105 mumol (100,000 IU) of [8,9,19-13C]retinyl palmitate in an oily solution.
D V Reinersdorff, E Bush, D J Liberato
doaj  

Alloferon and IL-22 receptor expression regulation on the pathogenesis of imiquimod-induced psoriasis

Scientific Reports
Psoriasis is an immune-mediated inflammatory skin disease. IL-22, a proinflammatory cytokine, is implicated in psoriasis pathogenesis; however, there is currently no established biological treatment targeting IL-22 or its receptor, IL-22Rα.
Tomoyo Agura, Hyejung Jo, Seulgi Shin, Yoojin Jang, Chong Won Choi, In Su Gwak, Jae Seung Kang, Yejin Kim   +7 more
doaj   +1 more source

Anti-Inflammatory Effects of Aptamin C in Pulmonary Fibrosis Induced by Bleomycin

Pharmaceuticals
Background/Objectives: Vitamin C is a well-known antioxidant with antiviral, anticancer, and anti-inflammatory properties. However, its therapeutic applications are limited by rapid oxidation due to heat and light sensitivity.
Seulgi Shin, Hyejung Jo, Tomoyo Agura, Seoyoun Jeong, Hyovin Ahn, Soyoung Pang, June Lee, Jeong-Ho Park, Yejin Kim, Jae Seung Kang   +9 more
doaj   +1 more source