Results 201 to 210 of about 939,048 (353)

ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy

Advanced Science, EarlyView.
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie, Tianyi Ji, Zixin Wan, Jie Huang, Han Li, Lingjiao Zou, Zhen Yang, Jiarui Li, Yuqi Guan, Lei Ruan, Jinhua Yan, Cuntai Zhang   +11 more
wiley   +1 more source

INTERRELATIONSHIPS AMONG VITAMIN B ₁₂ , AND METHIONINE AND ITS ANALOGUES, IN GROWTH OF ESCHERICHIA COLI AND IN BACTERIOPHAGE SYNTHESIS [PDF]

, 1958
Lloyd S. Lockingen, Ronald M. Humphrey, Orville Wyss   +2 more
openalex   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

The effects of vitamin B and D supplementations on autonomic functions and quality of life in children after vasovagal syncope. [PDF]

Front Pediatr
Kovalchuk T, Boyarchuk O, Balatska N.
europepmc   +1 more source

Antinociceptive effects of vitamin B-complex: A behavioral and histochemical study in rats. [PDF]

IBRO Neurosci Rep, 2023
Zarei SA, Shahriari-Khalaji M, Andolina IM, Behzadi G.   +3 more
europepmc   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

Advanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang   +9 more
wiley   +1 more source

Comparison of vitamin B levels in febrile children with and without febrile seizures: A prospective single-center study. [PDF]

Medicine (Baltimore)
Huang Y, Wen X, Guo H, Cao J.
europepmc   +1 more source

THE GROWTH-PROMOTING PROPERTIES (VITAMIN B COMPLEX) OF THE CONCENTRATED WATER-SOLUBLE PORTION OF MILK

, 1931
G.C. Supplee, O.J. Kahlenberg, G.E. Flanigan   +2 more
openalex   +1 more source

A Study of the Vitamin B Complex of Red Kidney Beans and Polished Rice [PDF]

, 1930
J. H. Axtmayer
openalex   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

Advanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen, Xiaokang Ma, Longlin Zhang, Hao Li, Jichang Zheng, Shengru Wu, Ke Zuo, Yulong Yin, Jing Wang, Bie Tan   +9 more
wiley   +1 more source