Results 201 to 210 of about 112,142 (312)

Premature closure underlies bias in medical diagnosis in students: A randomised controlled experiment

Medical Education, EarlyView.
Abstract Objective The purpose of the study reported in this article was to shed light on the cognitive mechanism mediating between biasing information and diagnostic error. The literature suggests at least two different hypotheses: premature closure leading biased participants to spend less time on diagnosis or increased competition between diagnostic
Awad Al Essa, Henk G. Schmidt, Silvia Mamede, Karla Knežević, Laura Zwaan, Mohi Magzoub   +5 more
wiley   +1 more source

Vitamin B12 Deficiency Presenting as Pseudothrombotic Microangiopathy and Intestinal Pseudo-Obstruction. [PDF]

Cureus
Salcedo Elguea EA, Barrio Rivera H, Garcia Chavez PA.   +2 more
europepmc   +1 more source

Naturally Occurring CodY Variants Alter Ligand Binding, DNA Target Affinity, and Virulence in Clostridioides difficile

Molecular Microbiology, EarlyView.
Single amino acid substitutions in the global regulator CodY can alter nutrient sensing and virulence regulation in Clostridioides difficile. We show that the CodY(Y146N) and CodY(V58A) variants display altered ligand binding and reduced promoter binding, leading to derepression of toxin regulatory pathways and increased virulence in vivo.
Md Kamrul Hasan, Sourav Roy, Revathi Govind   +2 more
wiley   +1 more source

Serum vitamin B12 levels and 90-day outcomes in hospitalized patients with dementia: A cohort study. [PDF]

Medicine (Baltimore)
Hsieh MH, Weng HL, Hung KC, Teng IC, Lai YC, Chen IW.   +5 more
europepmc   +1 more source

Chain‐Length Regulation by WzzE Is Necessary for, but Genetically Separable From, Cyclic Enterobacterial Common Antigen Synthesis

Molecular Microbiology, EarlyView.
Here, we demonstrate that polysaccharide chain length regulation plays a distinct role in enabling formation of a cyclic molecule important for the bacterial cell surface. However, this function is necessary, but not sufficient for the cyclic molecule's biosynthesis.
Joseph F. Carr, Yohannes H. Rezenom, Jennifer S. Rudolf, Daniel J. Warzecha, Angela M. Mitchell   +4 more
wiley   +1 more source

Investigating the Genetic Relationship Between Vitamin B12 Metabolism and Parkinson Disease. [PDF]

Neurol Genet
Dering R, Onvumere M, Liu L, Huot P, Gan-Or Z, Senkevich K.   +5 more
europepmc   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

Oral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier, Tim Hildebrandt, Ina Dewenter, Wenko Smolka, Eric Hesse, Philipp Poxleitner, Sven Otto   +6 more
wiley   +1 more source

Insights Into Subacute Combined Degeneration of the Cord: 'Rabbit Ear Sign' as a Radiodiagnostic Clue in Case of Vitamin B12 Deficiency Associated With Schizophrenia. [PDF]

Case Rep Neurol Med
Husnain M, Hasnat M, Nawaz A, Iqbal S, Numan A, Malik MA, Komal W, Sehar N, Nawaz R, Ali T, Farooq I.   +10 more
europepmc   +1 more source

Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung, Eirini Militsi, Olivier Huck   +2 more
wiley   +1 more source

Diagnostic challenge of high vitamin B12 levels: a case report and review of the literature. [PDF]

J Med Case Rep
Stella M, Sinico RA, Panvini FM, Manca A, Reggiani F, Calatroni M, Badalamenti S, Covini G.   +7 more
europepmc   +1 more source