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Vitamin B12 and the B12 Coenzymes
1995Publisher Summary Scientific investigations of the biochemistry of the structure and the mode of action of vitamin B12 have cleared up many of the puzzles regarding its medical relevance to pernicious anemia. Structural studies have revealed a complicated molecule with many sterically constrained areas, honed for efficient use by an enzyme that needs
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2005
The uptake of vitamin B12 from the intestine into the circulation is perhaps the most complex uptake mechanism of all the vitamins, involving no less than five separate VB12-binding molecules, receptors and transporters. Each molecule involved in uptake has a separate affinity and specificity for VB12 as well as a separate cell receptor.
G J, Russell-Jones, D H, Alpers
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The uptake of vitamin B12 from the intestine into the circulation is perhaps the most complex uptake mechanism of all the vitamins, involving no less than five separate VB12-binding molecules, receptors and transporters. Each molecule involved in uptake has a separate affinity and specificity for VB12 as well as a separate cell receptor.
G J, Russell-Jones, D H, Alpers
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Bioavailability of Vitamin B12
International Journal for Vitamin and Nutrition Research, 2010Vitamin B12 deficiency is common in people of all ages who consume a low intake of animal-source foods, including populations in developing countries. It is also prevalent among the elderly, even in wealthier countries, due to their malabsorption of B12 from food.
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International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1993
Chemicals/CAS: cyanocobalamin, 53570-76-6, 68-19-9, 8064-09-3; methylmalonic acid, 516-05-2; Methylmalonic Acid, 516-05-2; Vitamin B 12, 68-19 ...
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Chemicals/CAS: cyanocobalamin, 53570-76-6, 68-19-9, 8064-09-3; methylmalonic acid, 516-05-2; Methylmalonic Acid, 516-05-2; Vitamin B 12, 68-19 ...
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1954
Publisher Summary Soon after the epoch-making recognition of the effectiveness of whole liver therapy for the control of pernicious anemia, various groups of investigators carried out programs on the fractionation of liver extracts for the purification of the active principle.
K, FOLKERS, D E, WOLF
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Publisher Summary Soon after the epoch-making recognition of the effectiveness of whole liver therapy for the control of pernicious anemia, various groups of investigators carried out programs on the fractionation of liver extracts for the purification of the active principle.
K, FOLKERS, D E, WOLF
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2017
Cobalamin (vitamin B12) was discovered in the first half of the 20th century. Vast amount of information on the role of the vitamins in human health and disease became available. Cobalamin science was, however, based on theoretical concepts that have been accepted without further proof of facts and hypotheses.
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Cobalamin (vitamin B12) was discovered in the first half of the 20th century. Vast amount of information on the role of the vitamins in human health and disease became available. Cobalamin science was, however, based on theoretical concepts that have been accepted without further proof of facts and hypotheses.
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The biosynthesis of vitamin B12
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1976Abstract The use of 13C-Fourier transform nuclear magnetic resonance (F.t.-n.m.r.) has led to the observation that while 8 molecules of [2-13C] ALA are incorporated into vitamin B12 in P. shermanii, [5-13C]ALA labels only seven of the carbon atoms of cyanocobalamin, i.e.
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Oral vitamin b12 therapy in vitamin b12 deficiency
The American Journal of Medicine, 2004Mark, Roth, Israel, Orija
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