Results 21 to 30 of about 192,117 (300)
Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients [PDF]
, 2016 Purpose: Methotrexate administration is associated with frequent adverse neurological events during treatment for childhood acute lymphoblastic leukemia.
Baird, Susan F. +5 more
core +2 more sources
A case of Barrett's oesophagus in pernicious anaemia: acid is not the only culprit! [PDF]
, 2016 A 46-year-old female presented at our department with the onset of episodic dyspeptic symptoms, mainly postprandial fullness and bloating, as well as paresthesia.
Annibale, Bruno +3 more
core +1 more source
Involuntary movement in infants during vitamin B12 treatment
Turkish Journal of Hematology, 2011 Megaloblastic anemia is rare in infants and is generally due to vitamin B12 (cobalamin) deficiency in the mother. Neurologic symptoms of vitamin B12 deficiency include irritability, failure to thrive, hypotonia, and developmental regression/delay. Herein
Ayşe Tosun +4 more
doaj +3 more sources
, 2018 The biosynthesis of B12, involving up to 30 different enzyme-mediated steps, only occurs in bacteria. Thus, most eukaryotes require an external source of B12, and yet the vitamin appears to have only two functions in eukaryotes: as a cofactor for the enzymes methionine synthase and methylmalonylCoA mutase.
Smith, A. David +2 more
openaire +4 more sources
The importance of holotranscobalamin measurement [PDF]
Journal of Medical Biochemistry, 2007 Clinically significant vitamin B12 deficiency can occur even with total vitamin B12 levels apparently within normal range. There is an indeterminate zone between approximately 154 and 300 pmol/L of vitamin B12 where there is likely misclassification of ...
Čabarkapa Velibor +4 more
doaj
Trends in Pediatrics, 2022 Objective: Syncope is a frequent reason for referral to pediatric cardiology clinics. Vitamin B12 deficiency is frequently diagnosed in pediatric patients.
Süleyman Sunkak, Mustafa Argun
doaj +1 more source
Vitamin B12 deficiency among adult diabetic patients in Uganda: relation to glycaemic control and haemoglobin concentration [PDF]
, 2015 BACKGROUND: Vitamin B12 deficiency is highly prevalent among adult individuals with diabetes yet screening is infrequent in Uganda. There are currently no published data regarding the prevalence of vitamin B12 deficiency and its associated factors among ...
Christopher Opio +7 more
core +1 more source
Journal of Applied Hematology, 2018 Vitamin B12 is essential for DNA and RNA synthesis. Vitamin B12 deficiency usually occurs in infants who are exclusively breastfed born to Vitamin B12-deficient mothers.
K Jagadish Kumar +3 more
doaj +1 more source
Oral vitamin B12 for patients suspected of subtle cobalamin deficiency: a multicentre pragmatic randomised controlled trial [PDF]
, 2011 BACKGROUND: Evidence regarding the effectiveness of oral vitamin B12 in patients with serum vitamin B12 levels between 125-200 pM/l is lacking. We compared the effectiveness of one-month oral vitamin B12 supplementation in patients with a subtle vitamin ...
Bernard Burnand +7 more
core +3 more sources
RATEX: A Scalable RNA‐Based Platform for Logical and Multi‐Layered Cellular Programming
Angewandte Chemie, EarlyView.RATEX integrated ribosome‐mediated transcription control with synthetic RNA regulators, enabling simultaneous processing of RNA, metabolite, and small‐molecule inputs through complex logic operations within a single transcript. The platform achieves up to 1,492‐fold gene regulation, multi‐input hybrid logic gates, RNA‐programmed signaling cascades, and
Hyunseop Goh +3 more
wiley +2 more sources