Results 41 to 50 of about 449,639 (254)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical

Angewandte Chemie, EarlyView.
We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda, Alexander Umanzor, Julia Gartzke, Jeremy T. Maddigan‐Wyatt, Philipp Thielert, Stefan Weber, Sabine Richert, Shuming Chen, Daniel B. Werz   +8 more
wiley   +2 more sources

Gluten-Free Products Are Insufficient Source of Folate and Vitamin B12 for Coeliac Patients [PDF]

, 2011
Bezglutenska prehrana, jedini lijek za oboljele od celijakije, može biti neuravnotežena zbog nedostataka nekih hranjivih tvari. Bezglutenski proizvodi sadrže manju količinu vitamina B, osobito folata, nego slični proizvodi koji sadrže gluten.
Panjkota Krbavčić, Ines, Colić Barić, Irena, Bituh, Martina, Zadro, Zvonko, Žižić, Vesna   +4 more
core   +1 more source

Vitamin B12 status and skeletal muscle function among elderly: A literature review and pilot study on the effect of oral vitamin B12 supplementation in improving muscle function

Aging Medicine
Objectives The objective of this study is to understand the role of vitamin B12 supplementation in improving skeletal muscle function among the elderly.
Sowmya Sharma, Rohini Bhadra, Sumithra Selvam, Sucharita Sambashivaiah   +3 more
doaj   +1 more source

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE).
Sarah L. Patterson, Russell Ellyson, Jessica Fitzpatrick, Ghizlane Yaakoubi, Bradley Pearce, S. Sam Lim, Jinoos Yazdany, Laura C. Plantinga   +7 more
wiley   +1 more source

Vitamin B12 deficiency in an infant secondary to nutritional deficiency and an inadequate maternal diet. [PDF]

JPGN Rep
ABSTRACT Vitamin B12 (cobalamin, Cbl) is an essential micronutrient for DNA synthesis and neurological development. Its deficiency in infants, although infrequent in developed countries, can cause megaloblastic anemia, psychomotor delay, and neurological damage that may become irreversible if not treated early.
Sala-Lluch S, Mesas-Vila N, Ferrando-Monleón S, Barrés-Fernández A, Villar-Vera C, Arcos-Machancoses JV.   +5 more
europepmc   +2 more sources

Influence of vitamin B12 and light on the formation of chlorosomes in green- and brown-colored Chlorobium species [PDF]

, 1993
The specific Bchl a and c content of the vitamin B12-dependent Chlorobium limicola strain 1230 decreased strongly under vitamin B12 limitation. In comparison to a regularly grown culture (20 g vitamin B12/l) the specific Bchl c content of a B12-limited ...
Fischer, Ulrich, Fuhrmann, Sabine, Overmann, Jörg, Pfennig, Norbert, Jörg Overmann, Ulrich Fischer, Sabine Fuhrmann, Norbert Pfennig   +7 more
core   +1 more source

Serum Vitamin B12 Level of Children and Its Clinical Relationship with Febrile Seizures [PDF]

, 2023
Objective: In the present study, our aim was to investigate the correlation between vitamin B12 levels and febrile seizures (FS) in the pediatric population.
Okan Yüce, Övgü Böke, Hatice Sena Somuncu, Meltem Erol, Mehmet Tolga Köle, Abdulrahman Özel   +5 more
core   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Vitamin B12 deficiency and impaired expression of amnionless during aging

Journal of Cachexia, Sarcopenia and Muscle, 2018
Background Physical frailty and loss of mobility in elderly individuals lead to reduced independence, quality of life, and increased mortality. Vitamin B12 deficiency has been linked to several age‐related chronic diseases, including in the musculo ...
Alice Pannérec, Eugenia Migliavacca, Antonio De Castro, Joris Michaud, Sonia Karaz, Laurence Goulet, Serge Rezzi, Tze Pin Ng, Nabil Bosco, Anis Larbi, Jerome N. Feige   +10 more
doaj   +1 more source