Results 31 to 40 of about 424,620 (246)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Vitamin B12 status and skeletal muscle function among elderly: A literature review and pilot study on the effect of oral vitamin B12 supplementation in improving muscle function

Aging Medicine
Objectives The objective of this study is to understand the role of vitamin B12 supplementation in improving skeletal muscle function among the elderly.
Sowmya Sharma, Rohini Bhadra, Sumithra Selvam, Sucharita Sambashivaiah   +3 more
doaj   +1 more source

B vitamins and cognitive performance in older adults: Review [PDF]

, 2013
A copious amount of scientific scrutiny has been dedicated to documenting typical and atypical human ageing, with a substantial body of work focusing upon the impact of lifestyle choices.
Riby, Leigh, J. L. Reay, Reay, Jonathon, Reay, Jonathon L., L. M. Riby, M. A. Smith, Riby, L. M., Smith, Michael, Smith, Malcolm A.   +8 more
core   +1 more source

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults with Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective To characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE). Methods We analyzed cross‐sectional data from 451 adults in the Approaches to Positive, Patient‐centered Experiences of ...
Sarah L. Patterson, Russell Ellyson, Jessica Fitzpatrick, Ghizlane Yaakoubi, Bradley Pearce, S. Sam Lim, Jinoos Yazdany, Laura C. Plantinga   +7 more
wiley   +1 more source

Vitamin-B12 status among the mother–infant dyad: an explorative overview in a single centre in Lombardy

Frontiers in Nutrition
IntroductionMaternal vitamin B12 deficiency is an increasingly recognized cause of secondary neonatal cobalamin deficiency and can be incidentally detected through expanded newborn screening.MethodsWe retrospectively evaluated 240 infants and 238 mothers
Francesca Furlan, Francesco Tagliaferri, Francesco Tagliaferri, Stefano Mariani, Cristiana Berti, Simona Salera, Simona Lucchi, Simona Ferraro, Cristina Cereda, Cristina Cereda, Giulia Fiore, Giulia Fiore, Martina Tosi, Alice Spano, Alice Spano, Francesco Galandrini, Carlo Agostoni, Carlo Agostoni, Elvira Verduci, Elvira Verduci, Francesca Menni   +20 more
doaj   +1 more source

Vitamin B12 deficiency and impaired expression of amnionless during aging

Journal of Cachexia, Sarcopenia and Muscle, 2018
Background Physical frailty and loss of mobility in elderly individuals lead to reduced independence, quality of life, and increased mortality. Vitamin B12 deficiency has been linked to several age‐related chronic diseases, including in the musculo ...
Alice Pannérec, Eugenia Migliavacca, Antonio De Castro, Joris Michaud, Sonia Karaz, Laurence Goulet, Serge Rezzi, Tze Pin Ng, Nabil Bosco, Anis Larbi, Jerome N. Feige   +10 more
doaj   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Gluten-Free Products Are Insufficient Source of Folate and Vitamin B12 for Coeliac Patients [PDF]

, 2011
Bezglutenska prehrana, jedini lijek za oboljele od celijakije, može biti neuravnotežena zbog nedostataka nekih hranjivih tvari. Bezglutenski proizvodi sadrže manju količinu vitamina B, osobito folata, nego slični proizvodi koji sadrže gluten.
Panjkota Krbavčić, Ines, Colić Barić, Irena, Bituh, Martina, Martina Bituh, Zadro, Zvonko, Žižić, Vesna, Vesna Žižić, Zvonko Zadro, Irena Colić Barić, Ines Panjkota Krbavčić   +9 more
core   +1 more source

Assessment of vitamin B12 and homocysteine levels in pregnant women admitted for delivery and cord blood samples of their newborn babies: a multicenter study

The Turkish Journal of Pediatrics
Background. Vitamin B12, an indispensable micronutrient, is pivotal in numerous physiological processes, with particular significance during pregnancy and fetal development.
Zeynep Yıldız Yıldırmak, Dildar Bahar Genç, Alev Kural, Veli Mıhmanlı, Süleyman Salman, Keziban Doğan, Mehmet Ali Çiftçi, Nazlı Döktür Efeoğlu, Aliye Erdoğan, Neçirvan Çağdaş Çaltek, Emre Özgen, Ebru Kale   +11 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source