Results 81 to 90 of about 424,620 (246)

Multivariate modular metabolic engineering and medium optimization for vitamin B12 production by Escherichia coli

Synthetic and Systems Biotechnology
Vitamin B12 is a complex compound synthesized by microorganisms. The industrial production of vitamin B12 relies on specific microbial fermentation processes. E.
Feitao Chen, Huan Fang, Jianghua Zhao, Pingtao Jiang, Huina Dong, Ying Zhao, Huiying Wang, Tongcun Zhang, Dawei Zhang   +8 more
doaj   +1 more source

C. elegans MRP-5 Exports Vitamin B12 from Mother to Offspring to Support Embryonic Development

Cell Reports, 2018
Summary: Vitamin B12 functions as a cofactor for methionine synthase to produce the anabolic methyl donor S-adenosylmethionine (SAM) and for methylmalonyl-CoA mutase to catabolize the short-chain fatty acid propionate.
Huimin Na, Olga Ponomarova, Gabrielle E. Giese, Albertha J.M. Walhout   +3 more
doaj   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Association of maternal and cord vitamin B12 levels with anthropometry in term neonates born to malnourished mothers in coastal South India [version 2; peer review: 2 approved]

F1000Research
Background Malnourished pregnant women are at increased risk of micronutrient deficiency. We assessed the vitamin B12 status in both malnourished and normally nourished pregnant women and their neonates.
Poornima Manjrekar, Suchetha Rao, Sugapradha GR, Ramesh Holla   +3 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Vitamin B12 Deficiency Presenting as Pancytopenia in Pregnancy: A Case Report [PDF]

, 2012
Vitamin B12 deficiency is a well-known cause of megaloblastic anaemia and pancytopenia. However, the incidence in pregnancy is rarely reported. We present a case of a 32-year old multigravid woman who was diagnosed with megaloblastic anaemia since 22 ...
Idris N, Arsyad AH
core  

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

Influence of vitamin B12 and light on the formation of chlorosomes in green- and brown-colored Chlorobium species [PDF]

, 1993
The specific Bchl a and c content of the vitamin B12-dependent Chlorobium limicola strain 1230 decreased strongly under vitamin B12 limitation. In comparison to a regularly grown culture (20 g vitamin B12/l) the specific Bchl c content of a B12-limited ...
Fischer, Ulrich, Fuhrmann, Sabine, Overmann, Jörg, Pfennig, Norbert   +3 more
core   +1 more source

Rapid Restoration of Circulating Vitamin B12 Levels by Using Oral Sucrosomial^® Vitamin B12 in Metformin-Associated B12 Deficiency: Results from a Double-Blind, Placebo-Controlled Randomized Clinical Trial

Pharmaceutics
Background/Objectives: Vitamin B12 deficiency is common in individuals with type 2 diabetes mellitus (T2DM) receiving long-term metformin therapy, primarily due to impaired intestinal absorption.
Gabriele Conti, Allah W. Kalo, Ikram Ujjan, Aisha Aslam, Amjad Khan, Nazia M. Memon, Shair Z. Kakar, Naseer Ahmed, Shifa Zahid, Germano Tarantino, Elisa Brilli   +10 more
doaj   +1 more source

Body weight in autism spectrum disorder: A systematic review and meta‐analysis

JCPP Advances, EarlyView.
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz, Leyre Gambra, Samuele Cortese, Pablo Lizoain, Diana Rodriguez‐Romero, Ursula Paiva, Carmen Gándara, Sara Magallón, Gonzalo Arrondo   +8 more
wiley   +1 more source