Results 201 to 210 of about 19,308 (251)

Vitamin B3 and sirtuin function

Trends in Biochemical Sciences, 2005
Sirtuins are NAD(+)-dependent protein deacetylases that are involved in transcriptional regulation, metabolism, apoptosis, differentiation and ageing. These unique enzymes are inhibited by nicotinamide, which is a form of vitamin B3. Recent studies have uncovered the molecular basis for nicotinamide inhibition, and provided the framework to understand ...
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Vitamin B3, the nicotinamide adenine dinucleotides and aging

Mechanisms of Ageing and Development, 2010
Organism aging is a process of time and maturation culminating in senescence and death. The molecular details that define and determine aging have been intensely investigated. It has become appreciated that the process is partly an accumulation of random yet inevitable changes, but it can be strongly affected by genes that alter lifespan.
Ping, Xu, Anthony A, Sauve
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Vitamin B3 boosts neutrophil counts

Nature Medicine, 2009
A molecular pathway requiring vitamin B3 increases the production of neutrophils (pages 151–158). These findings could lead to new ways to treat neutropenias, diseases involving low neutrophil counts.
Arati Khanna-Gupta, Nancy Berliner
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Vitamin B3 protects mice from glaucoma

Science, 2017
Glaucoma Glaucoma is the most common cause of age-related blindness in the United States. There is currently no cure, and once vision is lost, the condition is irreversible. Williams et al. now report that vitamin B3 (also known as niacin) prevents eye degeneration in glaucoma-prone mice (see ...
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Vitamin B3 forms as precursors to NAD+: Are they safe?

Trends in Food Science & Technology, 2018
Abstract Background The oxidized form of cellular nicotinamide adenine dinucleotide (NAD+) is implicated in longevity, health improvement and even attenuation of some neurodegenerative processes. Immense interest of the public for anti-aging strategies and health-promoting lifestyle may result in increased use of NAD + precursors as food supplements.
B. Poljsak, I. Milisav
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NAD+ and Vitamin B3: From Metabolism to Therapies

The Journal of Pharmacology and Experimental Therapeutics, 2008
The role of NAD(+) metabolism in health and disease is of increased interest as the use of niacin (nicotinic acid) has emerged as a major therapy for treatment of hyperlipidemias and with the recognition that nicotinamide can protect tissues and NAD(+) metabolism in a variety of disease states, including ischemia/reperfusion.
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Vitamin B3 (niacin) in pregnancy and breastfeeding

2015
Niacin (as nicotinamide) is a component of coenzyme systems that function in the reductive biosynthesis of fatty acids and steroids, including cholesterol, and are involved in cell signalling. Niacin deficiency is rare, as the daily requirement can usually be met by food sources, and also via synthesis from tryptophan, which is present in dietary ...
Sir Peter Gluckman, Mark Hanson, Chong Yap Seng, Anne Bardsley   +3 more
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Vitamin B3

Disease-a-Month, 2003
Peter Jacobs, Lucille Wood
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Vitamin B3 in der kosmetischen Dermatologie

Aktuelle Dermatologie, 2017
ZusammenfassungNiacinamid ist der neue Trend bei den zellprotektiven Substanzen. Oral wird die Einnahme von 2 × 500 mg täglich empfohlen. Topisch wird die Substanz in 2 %-iger oder 5 %-iger Konzentration eingesetzt. Es blockiert die Hemmwirkung der UV-Strahlung auf die ATP-Produktion, fördert die DNA-Reparatur, reduziert aktinische Keratosen und ...
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