Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
Ascorbic Acid Levels in Vitamin Pills [PDF]
Although it is generally accepted that a balanced diet without supplementation contains enough vitamin C, it is still the most widely taken nutritional supplement world-wide.
Özmen, İbrahim Asutay
core +1 more source
The nutritional levels and status of vitamins among children in Henan, China
BackgroundVitamins are vital for children’s health, and deficiencies can cause disorders, compromising quality of life and survival. This study systematically assesses multivitamin levels, nutritional status, and associated factors in children from Henan,
Xiaojuan Li +6 more
doaj +1 more source
In present investigation, a comparative analysis of water soluble vitamins viz., B1 (thiamine HCl), B2 (riboflavin), B3 (nicotinamide), B5 (pantothenic acid), B6 (pyridoxine HCl), B9 (folic acid), B12 (cyanocobalamin) was carried out in fruits (immature,
Junaid Aslam +2 more
doaj +1 more source
Prenatal Vitamin D supplementation and child respiratory health: a randomised controlled trial [PDF]
Background Observational studies suggest high prenatal vitamin D intake may be associated with reduced childhood wheezing. We examined the effect of prenatal vitamin D on childhood wheezing in an interventional study.
Hooper Richard +47 more
core +1 more source
The genome and lifestage-specific transcriptomes of a plant-parasitic nematode and its host reveal susceptibility genes involved in trans-kingdom synthesis of vitamin B5 [PDF]
Plant-parasitic nematodes are a major, and in some cases a dominant, threat to crop production in all agricultural systems. The relative scarcity of classical resistance genes highlights a pressing need to identify new ways to develop nematode-resistant ...
Siddique, Shahid +4 more
core
Cotilédones obtidos a partir de sementes germinadas in vitro foram usados como explantes com o objetivo de avaliar o efeito de dois complexos vitamínicos e de duas concentrações de 6-benzilaminopurina (BAP) na organogênese direta do maracujá amarelo ...
Alessandra Ferreira Ribas +3 more
doaj +1 more source
Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung +12 more
wiley +1 more source
Stable isotope dilution techniques for assessing vitamin A status and bioefficacy of provitamin A carotenoids in humans. [PDF]
Vitamin A deficiency is a major global public health problem. Among the variety of techniques that are available for assessing human vitamin A status, evaluating the provitamin A nutritional values of foodstuffs and estimating human vitamin A ...
Judy D Ribaya-Mercado +19 more
core +1 more source
Synthetic Biology and Food: Applications and Prospects
Synthetic biology would provide revolutionary technological solutions to produce new food and feed components, such as artificial starch, animo acids, microbial protein, lipids, sweeteners, vitamins.
Yi‐Heng P. Job Zhang
wiley +1 more source

