Results 111 to 120 of about 49,291 (242)

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, Volume 13, Issue 31, 4 June 2026.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Clinical Profile and Plasma Vitamin B6 Levels in Children with Tourette Syndrome: A Case-control Study. [PDF]

Indian J Psychol Med
Kumar AA, Shaju A, Mubashira V, Balan S, Vidyadharan V, Dhananjayan D, Ravindren R.   +6 more
europepmc   +1 more source

Association between Vitamin E, Vitamin B6, and Vitamin B12 with coronary heart disease

Conflicting evidence still exists regarding Vitamin B12’s involvement in coronary heart disease (CHD). There is no precedent for previous studies to include both Vitamin B12, Vitamin B6, as well as Vitamin E in the consideration of CHD associating ...
Boyu Li, Dewei Wu, Xipeng Sun, Fuyu Jing, Yuanliang Ma, Mengjin Hu, Xiuling Wang   +6 more
core   +1 more source

Neuropathic Pain and Enlarged Nerves in Adult Noonan Syndrome and Noonan Syndrome With Multiple Lentigines: Health‐Related Quality of Life and Neurologic Symptoms

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1442-1451, June 2026.
ABSTRACT Noonan syndrome (NS) and the clinically related Noonan syndrome with multiple lentigines (NSML) belong to the group of RASopathies. Although pain is not mentioned as a characteristic feature, it has recently been reported as a clinically significant problem.
Jos M. T. Draaisma, Wesley Reintjes, Erika Leenders, Fieke Draaisma, Melanie Burgers, Lotte Kleimeier, Marco Tartaglia, Merel Klaassens, Ruud Becks, Steven Renes, Ellen Wingbermühle, Nicol C. Voermans, Nens van Alfen   +12 more
wiley   +1 more source

Carbidopa/levodopa induced severe vitamin B6 deficiency leading to symptomatic transfusion dependent microcytic Anemia. [PDF]

Oxf Med Case Reports
Lee BK, Gastwirt JP.
europepmc   +1 more source

Vitamins as potent cancer treatments through regulating the activity and expression of MMP‐2 and MMP‐9

Bulletin of the Korean Chemical Society, Volume 47, Issue 6, Page 745-755, June 2026.
Vitamins could regulate both MMP‐2 and MMP‐9 expression and activity through transcriptional and MAPK signaling pathway modulation. This study highlights the potential of vitamins as low‐toxicity therapeutic or adjunct agents for targeting MMP‐mediated cancer progression. Abstract Matrix metalloproteinases (MMP‐2 and MMP‐9) are key regulators of cancer
Yen Thi Nguyen, Eungchan Kim, Ha Vy Thi Vo, Song Ja Kim, Namdoo Kim, Hyuck Jin Lee   +5 more
wiley   +1 more source

Vitamin B6 (Pyridoxal 5' Phosphate) antagonises carotid body P2X3 receptors in hypertension. [PDF]

Cardiovasc Res
Felippe ISA, Babbage TL, Shaheen R, Bassetto M, Fan JL, Pauza A, Gold O, Thakkar P, Dawes M, Bates ML, McBryde F, Fountain SJ, Fisher JP, Paton JFR.   +13 more
europepmc   +1 more source

Bioenhancer‐Driven Modulation of Membrane Dynamics Improves B‐Vitamin Uptake in Caco‐2 Cells

ChemFoodChem, Volume 2, Issue 2, June 2026.
Natural bioenhancers such as extracts from ginger, turmeric, black pepper, and spearmint increase the uptake of vitamins B1, B5, B6, and B7 in Caco‐2 cells. Micellized formulations further increase efficacy. These findings indicate that altered membrane fluidity contributes to enhanced cellular absorption, providing a new route to improve vitamin B ...
Verena Preinfalk, Bernhard Blank‐Landeshammer, Marina Bishara, Sigrid Ihninger, Katja Essl, Stefanie Atzmüller, Mara Heckmann, Marcus Iken, Mario Brameshuber, Julian Weghuber   +9 more
wiley   +1 more source

Potential Role of Vitamin B6 as an Antioxidant via Pyridoxal-5'-Phosphate-Dependent Metabolic Pathways and Subsequent Activation of Nrf2 Signaling. [PDF]

Nutrients
Kato N, Yang Y, Khedara A, Kumrungsee T.
europepmc   +1 more source

Modeling the Impacts of Self‐Sufficiency Scenarios on Norwegian National Nutrient Supply

Climate Resilience and Sustainability, Volume 5, Issue 1, June 2026.
Food and nutrient flows through national food systems have important implications for national self‐sufficiency. Here, we examine food and nutrient flows through the Norwegian food system currently and under various possible scenarios. ABSTRACT As a part of the Norwegian strategy to meet the commitments they have made through international climate ...
Raquel Lozano, Nick William Smith, Katrine Lekang, Warren Charles McNabb   +3 more
wiley   +1 more source