Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial [PDF]
Background: B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke.
Al-Tahan +47 more
core +2 more sources
The study used the data from the National Health and Nutrition Examination Survey (NHANES) 2007–2014 to analyse the relationship of dietary vitamin B1, B2, niacin, B6, B12 and dietary folate equivalent (DEF) intakes with metabolic syndrome.
Yanjun Wu +3 more
semanticscholar +1 more source
Toward eradication of B-vitamin deficiencies : considerations for crop biofortification [PDF]
'Hidden hunger' involves insufficient intake of micronutrients and is estimated to affect over two billion people on a global scale. Malnutrition of vitamins and minerals is known to cause an alarming number of casualties, even in the developed world ...
Strobbe, Simon +1 more
core +3 more sources
Vitamin B6 and Its Role in Cell Metabolism and Physiology
Vitamin B6 is one of the most central molecules in cells of living organisms. It is a critical co-factor for a diverse range of biochemical reactions that regulate basic cellular metabolism, which impact overall physiology.
Marcelina Parra, S. Stahl, H. Hellmann
semanticscholar +1 more source
Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions [PDF]
Background: The phosphatase chronophin (CIN/PDXP) has been shown to be an important regulator of glioma cell migration and invasion. It has two known substrates: p-Ser3-cofilin, the phosphorylated form of the actin binding protein cofilin, and pyridoxal ...
Floßbach, Lucia +9 more
core +3 more sources
The in-vitro drug release study of vitamin B6 encapsulated into sodium tripolyphosphate crosslinked chitosan-alginate (B6-TCA) nanoparticles aims to determine the effect of sodium tripolyphosphate on the encapsulation efficiency of vitamin B6 and ...
Aulia Rahman +2 more
doaj +1 more source
The intestine plays a substantial role in human vitamin B6 metabolism: a Caco-2 cell model. [PDF]
BACKGROUND: Vitamin B6 is present in various forms (vitamers) in the diet that need to be metabolized to pyridoxal phosphate (PLP), the active cofactor form of vitamin B6.
Monique Albersen +8 more
doaj +1 more source
Preventive effect of vitamin B6 on developmental toxicity of carbamazepine in mice [PDF]
Objective(s): Carbamazepine (CBZ) is an antiepileptic drug that is used widely for the treatment of epileptic seizures. Neural tube defects (NTDs), growth retardation, and nail hypoplasia are the most common features of teratogenic effects of this drug ...
Afshar, M. +4 more
core +1 more source
Homocysteine in cerebrovascular disease: An independent risk factor for subcortical vascular encephalopathy [PDF]
Hyperhomocysteinemia is a risk factor for obstructive large-vessel disease. Here, we studied plasma concentrations of homocysteine and vitamins in patients suffering from subcortical vascular encephalopathy (SVE), a cerebral small-vessel disease leading ...
Aufenanger, Johannes +10 more
core +1 more source
Non-enzymatic hydrogen sulfide production from cysteine in blood is catalyzed by iron and vitamin B6
Hydrogen sulfide (H2S) plays important roles in metabolism and health. Its enzymatic generation from sulfur-containing amino acids (SAAs) is well characterized. However, the existence of non-enzymatic H2S production from SAAs, the chemical mechanism, and
Jie Yang +6 more
semanticscholar +1 more source

