Results 71 to 80 of about 340,270 (377)

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Screening for metabolic vitamin B₁₂ deficiency by holotranscobalamin in patients suspected of vitamin B₁₂ deficiency: a multicentre study [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2012
Background Vitamin B12 deficiency occurs frequently, especially among the elderly. However, screening for vitamin B12 deficiency is hampered by poor sensitivity of the existing total vitamin B12 assay. Methylmalonic acid (MMA) is considered as the most representative indicator of metabolic vitamin B12 deficiency and is used as such in this study.
Ton Rammeloo, J Maurits M Pekelharing, Maurits C.F.J. de Rotte, Robert de Jonge, Merel van Wijnen, Edward Sanders, Sandra G. Heil, Paul H Trienekens, Anneke C. Muller Kobold, Henk J Adriaansen, Rebecca M R Heiner-Fokkema, Jan Lindemans   +11 more
openaire   +4 more sources

Nitrous oxide myelopathy with functional vitamin B 12 deficiency

BMJ Case Reports, 2019
Recreational use of nitrous oxide as a ‘legal high’ is increasing in the UK. Physicians should be ‘street wise’ to this increasing prevalence and aware of the potential neurological complications which may result from misuse.
J. Williamson, S. Huda, Dinesh Damodaran
semanticscholar   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

The effect of Helicobacter pylori on vitamin B 12 blood levels in chronic renal failure patients: A single blind control trial

Saudi Journal of Kidney Diseases and Transplantation, 2013
Helicobacter pylori (HP) is a common infection worldwide and has been associated with severe morbidity. The level of vitamin B 12 in HP-infected chronic kidney disease (CKD) patients is reported to be lower than in the general population.
Hossein Khedmat, Mohsen Amini, Ashraf Karbasi, Reza Azizi   +3 more
doaj   +1 more source

VITAMIN D LEVELS IN PATIENTS WITH CHRONIC HEPATITIS B, CHRONIC HEPATITIS C, AND HEALTH CONTROLS [PDF]

Journal of IMAB, 2019
Purpose: Hepatitis B virus and Hepatitis C virus infection are the most common cause of acute and chronic hepatitis. Over the past decade, numerous studies reported that patients with chronic liver disease, especially HCV-positive and HBV-positive ...
Biljana Ilkovska, Bisera K. Trifunova, Sandra Hristovska, Marina Ivanovska   +3 more
doaj   +1 more source

Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study

Journal of Ideas in Health, 2021
Background: Folate and vitamin B 12 deficiency can lead to pancytopenia in pregnancy. Some cases of pancytopenia due to COVID-19 infection have also been reported.
Neha Agarwal, Neha Khatri, Preeti Singh
doaj   +1 more source

Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility12345 [PDF]

Approximately one-quarter of circulating cobalamin (vitamin B-12) binds to transcobalamin (holoTC) and is thereby available for the cells of the body. For this reason, holoTC is also referred to as active vitamin B-12.
Aarsetøy, Baker, Bamonti, Begley, Bleie, Bor, Bor, Brady, Carmel, Carmel, Carmel, Carmel, Castro, Clarke, Ebba Nexo, Elke Hoffmann-Lücke, Fedosov, Garrod, Green, Hardlei, Hardlei, Herbert, Herrmann, Herrmann, Herzlich, Hom, Hvas, Hvas, Hvas, Hvas, Kolhouse, Li, Lindemans, Lindgren, Lloyd-Wright, Loikas, Loikas, Miller, Moller, Morkbak, Morkbak, Morkbak, Murphy, Nexo, Nexo, Nexo, Nexo, Nexo, Nexo, Nexø, Nissen, Obeid, Orning, Platica, Quadros, Quadros, Refsum, Refsum, Schrempf, Skouby, Ulleland, van Kapel, von Castel-Roberts   +62 more
core   +2 more sources

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Study of Vitamin B 12 deficiency and peripheral neuropathy in metformin-treated early Type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2016
Background: Long-term therapy with metformin was shown to decrease the Vitamin B 12 level and manifested as peripheral neuropathy. Aim: The aim of this study is to define the prevalence of Vitamin B 12 deficiency in early Type 2 diabetic patients ...
Rudra Prasad Roy, Kaushik Ghosh, Manas Ghosh, Amitava Acharyya, Ambarish Bhattacharya, Mrinal Pal, Sisir Chakraborty, Nilanjan Sengupta   +7 more
doaj   +1 more source