Results 101 to 110 of about 92,834,848 (305)

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Vitamin A and iron supplementation of Indonesian pregnant women benefits vitamin A status of their infants [PDF]

, 2001
Many Indonesian infants have an inadequate nutritional status, which may be due in part to inadequate maternal nutrition during pregnancy. This study was designed to investigate whether infant nutritional status could be improved by maternal vitamin A ...
Muslimatun, S., West, C.E., Schultink, W., Schmidt, M.K., Hautvast, J.G.A.J.   +4 more
core   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Vitamin D Deficiency in Adults with Musculoskeletal Pain

, 2015
Objective: The aim of this study was to determine whether vitamin D deficiency in patients with musculoskeletal pain who were admitted to our hospital and to establish the difference between vitamin D levels according to gender and age groups ...
Roni Atalay, Sevgi Gümüş Atalay, Sinem Bozkurt, Özge Ardıçoğlu, Fatma Fidan, Berat Meryem Alkan, Hatice Aksekili, Ardicoglu, Ozge, Aksekili, Hatice, Atalay, Roni, Bozkurt, Sinem, Alkan, BERAT MERYEM, Atalay, Sevgi Gumus, Fidan, Fatma   +13 more
core   +1 more source

[Prevalence of vitamin B-12 deficiency in older adults]. [PDF]

, 2010
BACKGROUND: There is a correlation between aging and the decrease of plasma levels of vitamin B-12. AIM: To determine the prevalence of vitamin B-12 and folate deficiency and its hematological impact among older adults (AM).
Lavados Montes, Manuel, UAUY,RICARDO, Albala Brevis, Cecilia, Herlramp F, Eva, Lavados, Manuel, Uauy, Ricardo, ALBALA,CECILIA, Castillo, José Luis, Castillo Carrasco, José, LERA,LYDIA, LAVADOS,MANUEL, Verdugo, Renato, Lera, Lydia, CASTILLO,JOSÉ LUIS, Uauy Dagach-Imbarack, Ricardo, Hertrampf, Eva, VERDUGO,RENATO, Lera Marques, Lydia, SÁNCHEZ,HUGO, Verdugo Latorre, Renato, HERTRAMPF,EVA, Sánchez, Hugo, Albala, Cecilia   +22 more
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Can food-based strategies help reduce vitamin A and iron deficiencies? [PDF]

Micronutrient malnutrition is still a problem of unacceptable proportions in developing countries. Iron and vitamin A deficiencies are the most widespread nutrition deficiencies in the world today, affecting perhaps as many as 3.5 billion people ...
Ruel, Marie T.
core  

The Assessment of Vitamin D, Antimicrobial Peptides and Procalcitonin in Bronchiectasis [PDF]

, 2014
My research investigated the distribution of antimicrobial peptides (cathelicidin and β-defensin 2), vitamin D and the inflammatory marker procalcitonin, between systemic and localised respiratory levels in stable bronchiectasis patients.
Gartner, Sarah Nicole
core