Results 181 to 190 of about 525 (261)

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

A scoping review of quality prescribing indicators, rules and criteria for primary care

British Journal of Clinical Pharmacology, EarlyView.
Medication‐related problems (MRPs) place a substantial burden on the healthcare system, contributing to hospital admissions and significant healthcare costs. Quality prescribing indicators (QPIs), rules and criteria serve to educate prescribers about high risk MRPs and to monitor prescribing behaviours. This study aims to summarize existing indicators,
James Nind, Anna Mackintosh, Emma Maddock, Alana Delaforce, Gregory Peterson, Elizabeth Manias, Johnson George   +6 more
wiley   +1 more source

Asymmetric Dialysis: Truly Unified and Simultaneous Single‐Pass Concentration and Buffer Exchange

Biotechnology and Bioengineering, EarlyView.
Asymmetric dialysis, a novel one‐step continuous process combining ultrafiltration and diafiltration, achieves high product concentrations (up to 200 g/L) with low pressures and reduces buffer consumption by 75% compared to conventional methods. This sustainable, low‐cost technology demonstrates significant potential for integration into continuous ...
Ujwal Patil, Michelle Chen, Irina Ramos, Jon Coffman   +3 more
wiley   +1 more source

The influence of vitamin B[6] deficiency on mechanism of dimethylnitrosamine carcinogenesis

, 1994
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Vitamin B-6 Deficiency in Germfree Rats

The Journal of Nutrition, 1977
Germfree and conventional rats were used to investigate the influence of gut microflora upon vitamin B-6 deficiency. The body weights of conventional rats fed a vitamin B-6-deficient diet for more than 5 weeks plateaued, but the rats remained alive until the end of week 9 of deficiency.
Y, Sumi, M, Miyakawa, M, Kanzaki, Y, Kotake   +3 more
openaire   +2 more sources

Avoidance Behavior in Vitamin B-6-Deficient Rats

The Journal of Nutrition, 1975
Pyridoxine deficiency was induced during the postweaning period in infant and young adult male rats and the effects on active avoidance and escape learning were studied. Five weeks of pyridoxine deficiency was sufficient to produce a deficit in active avoidance learning in the postweanling animals, whereas up to 10 weeks of deficient diet ingestion ...
C N, Stewart, D B, Coursin, H N, Bhagavan   +2 more
openaire   +2 more sources

Vitamin B 1, B 2 and B 6 deficiency in neurological disorders

Journal of Neurology, 1981
The activities of the red blood cell enzymes transketolase, glutathione reductase, and glutamic oxaloacetate transaminase were measured with and without in vitro addition of their respective coenzyme components thiamine, riboflavin, and pyridoxine in a group of patients with neurological disorders which may have been caused by malnutrition, intestinal ...
H D, Langohr, F, Petruch, G, Schroth
openaire   +2 more sources

Konjac Mannan Improves the Vitamin B-6 Status of Rats Fed a Vitamin B-6-deficient Diet

International Journal for Vitamin and Nutrition Research, 1999
To investigate how dietary fiber in the diet affects vitamin B-6 nutriture of rats which have been deprived of vitamin B-6, rats were made vitamin B-6-deficient by feeding a vitamin B-6-deficient 70% casein diet. They were fed 2% cellulose powder-based vitamin B-6-deficient diets supplemented with 3% of additional dietary fiber sources (agar, konjac ...
T, Hayakawa, Y, Iida, H, Tsuge
openaire   +2 more sources

Methionine Transamination and Catabolism in Vitamin B-6 Deficient Rats

The Journal of Nutrition, 1979
G. BELI VEAU EVERETT,2 A. D. MITCHELL 3ANDN. J. BENEVENGADepartments of Nutritional Sciences and Meat andAnimal Science, University of Wisconsin,Madison, Wisconsin 53706ABSTRACT Methionine (Met) transamination and oxidation of theMet or a-keto-y-methiolbutyrate (aKyMB) carboxyl and methyl carbonswere studied in weanling rats fed control or vitamin B8 ...
G B, Everett, A D, Mitchell, N J, Benevenga   +2 more
openaire   +2 more sources