Metformin and vitamin B12 deficiency: What is the evidence? [PDF]
The widespread adoption of metformin as a primary therapeutic agent for type 2 diabetes has prompted inquiries into its potential impact on vitamin B 12 (cobalamin) levels and subsequent deficiency. This study aimed to elucidate this complex relationship
Oliveira Peixoto Bruno Daniel +3 more
doaj +1 more source
Toxicoproteomic Profiling of hPXR Transgenic Mice Treated with Rifampicin and Isoniazid
Tuberculosis is a global health threat that affects millions of people every year, and treatment-limiting toxicity remains a considerable source of treatment failure.
Christopher Trent Brewer +5 more
doaj +1 more source
Vitamin D, innate immunity and outcomes in community acquired pneumonia [PDF]
We investigated the associations between vitamin D status, the antimicrobial peptides cathelicidin and beta defensin-2 and outcomes in community acquired pneumonia.
Karalus, Noel +9 more
core +1 more source
A randomised controlled trial investigating the effect of vitamin B12 supplementation on neurological function in healthy older people: the Older People and Enhanced Neurological function (OPEN) study protocol [ISRCTN54195799]. [PDF]
BACKGROUND: Vitamin B12 deficiency is common in older people and the prevalence increases with age. Vitamin B12 deficiency may present as macrocytic anaemia, subacute combined degeneration of the spinal cord, or as neuropathy, but is often asymptomatic ...
Allen, Elizabeth +21 more
core +2 more sources
Vitamin D deficiency in chronic obstructive pulmonary disease and bronchogenic carcinoma
Rationale Vitamin D has been known to have an important role as an anti-inflammatory agent and immune modulator. The aim of this work was to evaluate the impact of vitamin D deficiency on chronic obstructive pulmonary disease (COPD) and bronchogenic ...
Yasmine H El-Hinnawy +2 more
doaj +1 more source
Effectiveness of the National Program of Complementary Feeding for older adults in Chile on vitamin B12 status in older adults; secondary outcome analysis from the CENEX Study (ISRCTN48153354). [PDF]
BACKGROUND: Older people are at increased risk of vitamin B12 deficiency and the provision of fortified foods may be an effective way to ensure good vitamin B12 status in later life.
Sánchez Reyes, Hugo +15 more
core +2 more sources
We are reporting monochorionic, diamniotic twin premature infants born at 25 weeks and 6 days gestation with riboflavin (vitamin B2) and biotin (vitamin B7) deficiency, while on prolonged total parenteral nutrition (TPN) during vitamin shortage.
Mohammad Amin Adie MD +7 more
doaj +1 more source
Background/aim: Frailty is increasingly recognized as a relevant prognostic factor in patients with cirrhosis, regardless of liver failure. Vitamin D deficiency is frequent in these patients and has been related to frailty and sarcopenia, but the impact ...
Raquel Díaz-Ruíz +13 more
doaj +1 more source
Vitamin D and endothelial function in chronic kidney disease [PDF]
PhDVitamin D deficiency in patients with chronic kidney disease, measured by reduced serum concentrations of 25 hydroxy vitamin D, is highly prevalent and associated with both endothelial dysfunction and an increased risk of cardiovascular disease ...
Dreyer, Gavin
core +2 more sources
Dental Implants Rehabilitation in Patients with Vitamin D3 Imbalance: A Randomized Controlled Trial
Background: Vitamin D3 is an important factor for bone metabolism, and its deficiency may affect dental implantation results. Materials and methods: 384 patients with a diagnosis of tooth loss and vitamin D deficiency were examined and treated with ...
Ekaterina Diachkova +13 more
doaj +1 more source

