Results 41 to 50 of about 166,414 (214)

Causal relationships of familial hypercholesterolemia with the risk of multiple vitamin deficiencies: a Mendelian randomization study

Frontiers in Endocrinology
BackgroundThe causal relationship between familial hypercholesterolemia (FH) and various vitamin deficiencies has not yet been elucidated. Therefore, this study investigated the cause-and-effect relationship between FH and the risk of multiple vitamin ...
Cheng Zhang, Gang Wei, Huan Zhou, Lin Liu   +3 more
doaj   +1 more source

Detectable Unmetabolized Folic Acid and Elevated Folate Concentrations in Folic Acid-Supplemented Canadian Children With Sickle Cell Disease

Frontiers in Nutrition, 2021
Sickle cell disease (SCD) is an inherited hemoglobinopathy caused by a variant (rs344) in the HBB gene encoding the β-globin subunit of hemoglobin. Chronic hemolytic anemia and increased erythropoiesis and RBC turnover in individuals with SCD can result ...
Brock A. Williams, Brock A. Williams, Cara Mayer, Cara Mayer, Heather McCartney, Angela M. Devlin, Angela M. Devlin, Yvonne Lamers, Yvonne Lamers, Suzanne M. Vercauteren, Suzanne M. Vercauteren, John K. Wu, John K. Wu, Crystal D. Karakochuk, Crystal D. Karakochuk   +14 more
doaj   +1 more source

Functional and Metabolic Consequences of Vitamin B-6 Deficiency in the Rat Heart

Experimental Biology and Medicine, 1987
The cardiac functional and metabolic consequences of pyridoxine deficiency were studied in rats maintained on a pyridoxine-deficient diet for 10 weeks. Because food intake was diminished in the pyridoxine-deficient rats, a second group of animals was fed a diet restricted to the intake of the pyridoxine-deficient animals.
Feldman, Arthur M., Guilarte, Tomas R., Baughman, Kenneth L., Gerstenblith, Gary   +3 more
openaire   +2 more sources

The effects of vitamin D supplementation on the incidence of pneumonia in infants and young children in Kabul, Afghanistan: a double blind randomized controlled trial [PDF]

Afghanistan has one of the highest infant mortalities in the world, and pneumonia is one of the main killers. Moreover, Dietary intake of vitamin D is low and exposure to sunlight is limited due to widespread use of Burqa by women.
Maroof, Zabihullah
core   +1 more source

Month of birth, vitamin D and risk of immune mediated disease: a case control study [PDF]

, 2012
: BACKGROUND: A season of birth effect in immune-mediated diseases (ID) such as multiple sclerosis and type 1 diabetes has been consistently reported. We aimed to investigate whether season of birth influences the risk of rheumatoid arthritis, Crohn's ...
Chaplin, G, Giovannoni Gavin, Giulio Disanto, Gavin Giovannoni, Morahan, JM, Ramagopalan, SV, Chaplin George, Hyppönen Elina, Ebers George C, Hyppoenen, E, Elina Hyppönen, Ramagopalan, Sreeram, George C Ebers, Disanto Giulio, Sreeram V Ramagopalan, Ebers, GC, George Chaplin, Ramagopalan Sreeram V, Julia M Morahan, Morahan Julia M, Ebers, George, Giovannoni, G, Disanto, G, Hypponen, E   +23 more
core   +1 more source

Generalized Developmental Enamel Hypoplasia of the Permanent Dentition Associated with Early Childhood Vitamin D Deficiency Rickets: A Case Report

Dentistry Journal
Background: Vitamin D deficiency rickets is a metabolic bone disorder caused by impaired calcium and phosphate homeostasis resulting from insufficient vitamin D. In children, severe vitamin D deficiency can disturb the mineralization of growing bones and
Rena Okawa, Misato Takagi, Yuto Suehiro, Kazuhiko Nakano   +3 more
doaj   +1 more source

Decreased vitamin B 12 and folic acid concentrations in acne patients after isotretinoin therapy: A controlled study

Indian Journal of Dermatology, 2014
Background: Oral isotretinoin treatment might influence the levels of vitamin B 12 and folic acid. Aims and Objectives: The aim of this study is to compare vitamin B 12 and folic acid levels in patients with moderate and severe acne vulgaris with those ...
Hilal Gökalp, I Bulur, M A Gürer
doaj   +1 more source

Circulating Vitamin D levels status and clinical prognostic indices in COVID-19 patients

Respiratory Research, 2021
Background Several immune mechanisms activate in COVID-19 pathogenesis. Usually, coronavirus infection is characterized by dysregulated host immune responses, interleukine-6 increase, hyper-activation of cytotoxic CD8 T lymphocytes.
Alberto Ricci, Alessandra Pagliuca, Michela D’Ascanio, Marta Innammorato, Claudia De Vitis, Rita Mancini, Simonetta Giovagnoli, Francesco Facchiano, Bruno Sposato, Paolo Anibaldi, Adriano Marcolongo, Chiara De Dominicis, Andrea Laghi, Emanuele Muscogiuri, Salvatore Sciacchitano   +14 more
doaj   +1 more source

Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]

, 2011
Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Wu, Shaoping, Jae-Woong Hwang, Sundar, Isaac K, Sun, Jun, Isaac K. Sundar, Hwang, Jae-woong, Rahman, Irfan, Shaoping Wu, Irfan Rahman, Jun Sun   +9 more
core   +1 more source

Underlying factors associated with anemia in Amazonian children: a population-based, cross-sectional study.

PLoS ONE, 2012
BackgroundAlthough iron deficiency is considered to be the main cause of anemia in children worldwide, other contributors to childhood anemia remain little studied in developing countries.
Marly A Cardoso, Kézia K G Scopel, Pascoal T Muniz, Eduardo Villamor, Marcelo U Ferreira   +4 more
doaj   +1 more source