Results 41 to 50 of about 319,241 (311)

Interactions and potential implications of Plasmodium falciparum-hookworm coinfection in different age groups in south-central Côte d'Ivoire [PDF]

, 2012
BACKGROUND: Given the widespread distribution of Plasmodium and helminth infections, and similarities of ecological requirements for disease transmission, coinfection is a common phenomenon in sub-Saharan Africa and elsewhere in the tropics. Interactions
A Spiegel, AA Righetti, AH Shankar, Ahou-Yah G. Koua, Aurélie A. Righetti, C Menendez, CJL Murray, D Filmer, DA Ross, DI Thurnham, DL Doolan, Dominik Glinz, EK N'Goran, EK N'Goran, Eliézer K. N'Goran, FC Hartgers, FK Grant, FP Mockenhaupt, Francis Mutuku, G Jones, G Weiss, GC Melo, HR Choudhury, J Langhorne, J Murray, JD Cook, JG Erhardt, JK Kung'u, JL Gorstein, Jürg Utzinger, KE Lyke, KP West Jr, L Brutus, L Serghides, Lukas G. Adiossan, M Nacher, M Zuk, MD Taylor, N Katz, NJ Yatich, NR de Silva, P Galan, PJ Hotez, Richard F. Hurrell, Rita Wegmüller, RJ Stoltzfus, RL Pullan, RM Maizels, RW Snow, S Brooker, S Brooker, SL Becker, Sébastien Niamké, Y Dror   +53 more
core   +2 more sources

Circulating Vitamin D levels status and clinical prognostic indices in COVID-19 patients

Respiratory Research, 2021
Background Several immune mechanisms activate in COVID-19 pathogenesis. Usually, coronavirus infection is characterized by dysregulated host immune responses, interleukine-6 increase, hyper-activation of cytotoxic CD8 T lymphocytes.
Alberto Ricci, Alessandra Pagliuca, Michela D’Ascanio, Marta Innammorato, Claudia De Vitis, Rita Mancini, Simonetta Giovagnoli, Francesco Facchiano, Bruno Sposato, Paolo Anibaldi, Adriano Marcolongo, Chiara De Dominicis, Andrea Laghi, Emanuele Muscogiuri, Salvatore Sciacchitano   +14 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Association of Vitamin D3 Level with Breast Cancer Risk and Prognosis in African-American and Hispanic Women. [PDF]

, 2017
Background: This study investigated the association of vitamin D3 levels with breast cancer risk and progression in African-Americans and Hispanics. Methods: A total of 237 African-American (Cases = 119, Control = 118) and 423 Hispanic women (Cases = 124,
Chlebowski, Rowan, Clayton, Sheilah, Sarkissyan, Marianna, Vadgama, Jaydutt V, Wu, Yanyuan   +4 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Causal relationships of familial hypercholesterolemia with the risk of multiple vitamin deficiencies: a Mendelian randomization study

Frontiers in Endocrinology
BackgroundThe causal relationship between familial hypercholesterolemia (FH) and various vitamin deficiencies has not yet been elucidated. Therefore, this study investigated the cause-and-effect relationship between FH and the risk of multiple vitamin ...
Cheng Zhang, Gang Wei, Huan Zhou, Lin Liu   +3 more
doaj   +1 more source

Decreased vitamin B 12 and folic acid concentrations in acne patients after isotretinoin therapy: A controlled study

Indian Journal of Dermatology, 2014
Background: Oral isotretinoin treatment might influence the levels of vitamin B 12 and folic acid. Aims and Objectives: The aim of this study is to compare vitamin B 12 and folic acid levels in patients with moderate and severe acne vulgaris with those ...
Hilal Gökalp, I Bulur, M A Gürer
doaj   +1 more source

Kynurenine metabolism in vitamin-B-6-deficient rat liver after tryptophan injection [PDF]

Biochemical Journal, 1984
Tryptophan contents of liver, serum and kidney were determined in normal and vitamin-B-6-deficient rats after tryptophan injection. Tryptophan contents of normal and B-6-deficient liver were different, but not those in serum and kidney. Both kynurenine and 3-hydroxykynurenine accumulated in B-6-deficient liver more than in the normal.
F, Takeuchi, Y, Shibata
openaire   +2 more sources

Elimination of avoidable blindness due to cataract: where do we prioritize and how should we monitor this decade? [PDF]

, 2012
BACKGROUND: In the final push toward the elimination of avoidable blindness, cataract occupies a position of eminence for the success of the Right to Sight initiative. AIMS: Review existing situation and assess what monitoring indicators may be useful to
John, Neena, Murthy, Gudlavalleti VS, Pant, Hira B, Shamanna, Bindiganavale R   +3 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source