Results 251 to 260 of about 1,109,158 (332)

Vitamin C enhances corneal fungal infection treatment in mice via chemotaxis and anti-inflammation. [PDF]

Antimicrob Agents Chemother
Xie Y, Jian S, Yue J, Wang C, Dong J, He S, Liu S, Wang L, Zhang H.   +8 more
europepmc   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

Neurodevelopmental Changes in the Guinea Pig Brain Caused by Time-Limited Complete Vitamin C Deprivation. [PDF]

Nutrients
Čapo I, Andrijević I, Čapo N, Popović M, Milenković I, Ratajac R, Vranješ D, Milutinović D, Simin D, Sekulić S.   +9 more
europepmc   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Loss of TET2 activity limits the ability of vitamin C to activate DNA demethylation in human HAP1 cells. [PDF]

Epigenetics Chromatin
Gawronski M, Starczak M, Wasilow A, Dziaman T, Olinski R, Gackowski D.   +5 more
europepmc   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

High-dose vitamin C as a targeted treatment for KRAS-driven cancers? [PDF]

Redox Biol
Mack E, Rau C, Otet C, Schäfer JA, Brendel C, Grass A, Bredow P, Hohl C, Denkert C, Willeke F, Neubauer A.   +10 more
europepmc   +1 more source

C-reactive protein, vitamin B12 and C677T polymorphism of N-5,10-methylenetetrahydrofolate reductase gene are related to insulin resistance and risk factors for metabolic syndrome in Chinese population

, 2010
Ai-Rong Chen, Honggang Zhang, Zhiping Wang, Sheng-Jun Fu, Peiqi Yang, Jiangong Ren, Ying-Yuan Ning, Xuejian Hu, Ling-Hong Tian   +8 more
openalex   +2 more sources

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

Advanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

The Influence of Vitamin C-incorporated Polycaprolactone on Osteogenesis in Osteoblast-Osteoclast Co-culture In Vitro. [PDF]

Int Dent J
Abdulhameed EA, Rani KGA, Neel EAA, Khalifa N, Johari Y, Omar M, Samsudin AR.   +6 more
europepmc   +1 more source