Results 111 to 120 of about 17,019,648 (385)

Vitamin D sensitivity to the immune responses and autoimmunity: A chemical network model study [PDF]

open access: yesarXiv, 2013
Although Vitamin D is believed to be involved in a large number of immune responses our understanding of these processes at cellular level remained at infancy. We develop and solve a coarse grained kinetic network model to quantify the effects of variation of vitamin D on human immunity. The system of equations accounts for known inter-relation between
arxiv  

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo   +11 more
wiley   +1 more source

Calculation of the Sun exposure time for the synthesis of vitamin D in Urcuquí, Ecuador [PDF]

open access: yesProceeding of Abstracts of IWBBIO, Francisco Ortu\~no Guzm\'an, Ignacio Rojas Ru\'iz (Comp.), ISBN: 978-84-16929-58-0 (2017), 27, 2017
The synthesis of vitamin D is strongly linked to the availability of solar energy. For a long time, it was clear that using the erythemal irradiances is a good choice to calculate the exposure time. Several authors argue that this method of minimum exposure time overestimates the calculation of the solar irradiance of vitamin D.
arxiv  

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Global vitamin D status problems: causes, pathogenetic mechanisms, treatment, prevention measures

open access: yesМедицинский совет, 2018
There is a need to improve the status of vitamin D. Vitamin D not only affects the processes of formation of the musculoskeletal system, but also actively participates in many extra-osseous effects of cholecalciferol.
N. A. Buralkina   +2 more
doaj   +1 more source

Comparative analysis of vitamin D content in sardines canned in olive oil and water [PDF]

open access: yes, 2016
Vitamin D is a fat-soluble hormone primarily responsible in maintaining plasma calcium and phosphorus homeostasis in humans. Vitamin D insufficiency and deficiency is a global health issue.
Kalajian, Tyler Arek
core   +1 more source

Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface [PDF]

open access: yes, 2009
Plasma concentrations of biologically active vitamin D (1,25- (OH)2D) are tightly controlled via feedback regulation of renal 1-hydroxylase (CYP27B1; positive) and 24-hydroxylase (CYP24A1; catabolic) enzymes.
Albertson   +101 more
core   +3 more sources

A repeated measures approach to pooled and calibrated biomarker data [PDF]

open access: yesarXiv, 2021
Participant level meta-analysis across multiple studies increases the sample size for pooled analyses, thereby improving precision in effect estimates and enabling subgroup analyses. For analyses involving biomarker measurements as an exposure of interest, investigators must first calibrate the data to address measurement variability arising from usage
arxiv  

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

open access: yesAdvanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar   +4 more
wiley   +1 more source

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