Results 251 to 260 of about 809,352 (389)

Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas: A Randomized Clinical Trial

open access: yesJAMA Oncology, 2017
Elizabeth L. Barry   +6 more
semanticscholar   +1 more source

Accessing the impact of harvest weights of Tenebrio molitor on amino acid digestibility and metabolizable energy in cecectomized laying hens

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 665-674, 15 January 2026.
Abstract BACKGROUND The effects of harvest weights on composition, amino acid (AA) digestibility and metabolizable energy (MEN) of Tenebrio molitor (TM) were investigated using cecectomized laying hens. The partially defatted and dried TM variants comprised median individual frass‐free harvest weights of 60, 80, 100, and 120 mg of larvae, and a pupae ...
Adewunmi Omotoso   +4 more
wiley   +1 more source

Lysophosphatidic Acid Synergizes With 1,25‐Dihydroxyvitamin D to Promote Fibroblast Growth Factor‐23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay   +7 more
wiley   +1 more source

Vitamin D3 encapsulated in polymeric nanoparticles to dampen the pro-inflammatory immune response. [PDF]

open access: yesJ Transl Autoimmun
Minnee J   +5 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang   +6 more
wiley   +1 more source

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