Results 251 to 260 of about 809,352 (389)
Abstract BACKGROUND The effects of harvest weights on composition, amino acid (AA) digestibility and metabolizable energy (MEN) of Tenebrio molitor (TM) were investigated using cecectomized laying hens. The partially defatted and dried TM variants comprised median individual frass‐free harvest weights of 60, 80, 100, and 120 mg of larvae, and a pupae ...
Adewunmi Omotoso +4 more
wiley +1 more source
The first step for understanding the molecular mechanism of the antifibrotic effect of inhaling 25(OH)-vitamin D3 and 1,25(OH)<sub>2</sub>-vitamin D3 in the murine model of hypersensitivity pneumonitis. [PDF]
Lemieszek MK +7 more
europepmc +1 more source
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay +7 more
wiley +1 more source
Vitamin D3 encapsulated in polymeric nanoparticles to dampen the pro-inflammatory immune response. [PDF]
Minnee J +5 more
europepmc +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source

