Results 181 to 190 of about 14,972,601 (255)

The potency of native postbiotics and paraprobiotics in modulating inflammation by affecting the gut–kidney axis

Animal Models and Experimental Medicine, EarlyView.
Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani, Mahnaz Torfeh, Fatemeh Ashrafian, Niloofar Rezaie, Mohsen Mohammadi, Shadi Aghamohammad, Mahdi Rohani   +6 more
wiley   +1 more source

Modular Access to α‐Tertiary Amines: Electrochemical Tandem Di‐Functionalization of Olefins With Ammonia Surrogates and Amino Acids

Angewandte Chemie, EarlyView.
A metal‐ and oxidant‐free electrochemical multicomponent di‐functionalization strategy that rapidly converts 1,1‐disubstituted alkenes into α‐tertiary primary amines with simultaneous installation of bio‐relevant sulfur or selenium motifs was devised for late‐stage functionalization. ABSTRACT Quaternary carbon centers, especially those bearing nitrogen,
Adrija Ghosh, Tarun, Sven Erik Peters, Lutz Ackermann, Debasis Banerjee   +4 more
wiley   +2 more sources

SARS-CoV-2 infection induces functional impairment of vitamin D receptor signaling to drive interleukin 6-dependent hyperinflammation in mononuclear phagocytes. [PDF]

PLoS One
Valdés-López JF, di Filippo D, Penagos S, Hernández-Sarmiento LJ, Arroyave-Ospina JC, Rojas M, Urcuqui-Inchima S, Aguilar-Jiménez W, Navas MC.   +8 more
europepmc   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Vitamin D receptor (VDR) expression in osteosarcoma and its association with histological subtypes and metastasis. [PDF]

Sci Rep
Baly I, Sulistyoningrum DC, Putro YAP, Widodo I, Dwianingsih EK.   +4 more
europepmc   +1 more source

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

Annals of Neurology, EarlyView.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini, Sean J. Pittock, Laura Cacciaguerra, Howard L. Weiner, Luke A. Schwerdtfeger   +4 more
wiley   +1 more source

Impact of vitamin D receptor gene variants on psoriasis vulgaris susceptibility and clinical phenotype in a Greek population. [PDF]

Exp Ther Med
Sidiropoulou P, Katsarou M, Papasavva M, Tsolakou A, Fotiadis A, Spandidos DA, Rompoti N, Stefanaki I, Stratigos AJ, Drakoulis N, Nicolaidou E.   +10 more
europepmc   +1 more source

Vitamin D receptor isoform VDRA suppresses hepatocellular tumorigenesis by restricting YAP nuclear localization. [PDF]

Cell Death Dis
Li L, He S, Wang R, Wang J, Zheng Z, Wang Z, Li B, Ye W, Wang P.   +8 more
europepmc   +1 more source

Synthetic Modulators of the Vitamin D Receptor: From Structural Innovation to Disease-Specific Applications. [PDF]

Biomolecules
Nguyen TT, Kurokawa T, Kanemoto Y, Sawada T, Kato S.   +4 more
europepmc   +1 more source

Association Between SNAIL1 Gene Expression, SNAIL1 Genetic Variation, Vitamin D Receptor Gene Expression, and Vitamin-D Status Among Jordanian Asthmatic Patients. [PDF]

J Multidiscip Healthc
Zatar AM, Jarrar YB, Hindash ZK, Albtoosh AS, Al-Younes AH, Imraish AM, Hakooz N.   +6 more
europepmc   +1 more source