Long-term follow-up for mortality and cancer in a randomized placebo-controlled trial of vitamin D3 and/or calcium (RECORD Trial) [PDF]
Context: Vitamin D or calcium supplementation may have effects on vascular disease and cancer. Objective: Our objective was to investigate whether vitamin D or calcium supplementation affects mortality, vascular disease, and cancer in older people ...
McDonald, AM +54 more
core +1 more source
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Yogurt drink fortified with menaquinone-7 improves vitamin K status in a healthy population
Population-based studies have shown an inverse association between dietary menaquinones (MK-n, vitamin K2) intake, coronary calcification and CHD risk, suggesting a potential role of vitamin K in vascular health.
Marjo H. J. Knapen +5 more
doaj +1 more source
Stable isotope dilution techniques for assessing vitamin A status and bioefficacy of provitamin A carotenoids in humans. [PDF]
Vitamin A deficiency is a major global public health problem. Among the variety of techniques that are available for assessing human vitamin A status, evaluating the provitamin A nutritional values of foodstuffs and estimating human vitamin A ...
Judy D Ribaya-Mercado +19 more
core +1 more source
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang +9 more
wiley +1 more source
Vitamin D and innate immunity in pneumonia and COPD
A resurgence of interest in vitamin D research has led to the discovery that it plays a role in an unexpectedly large number of biological processes, and that reduced levels of this hormone are implicated in a range of diseases.
Simpson, Talia Mary
core
Climate Change Threatens Micronutrient Density of European Winter Wheat
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao +17 more
wiley +1 more source
The experimentally investigations on acute ivarfarine poisoned dogs and lambs and its treatment [PDF]
This study has been madein order to fihd out the effect of Transamin (an antifibrinolitic medicine) with Vitamin K1 and to observe elinical and haematological changes on dogs and one year old lambs which experimentally poisoned by an anticoagulant ...
Veysi ASLAN
doaj
Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang +12 more
wiley +1 more source

