Results 1 to 10 of about 277,539 (261)

Links between Vitamin K, Ferroptosis and SARS-CoV-2 Infection

Antioxidants, 2023
Ferroptosis is a recently discovered form of programmed cell death. It is characterized by the accumulation of iron and lipid hydroperoxides in cells.
Jarosław Nuszkiewicz, Paweł Sutkowy, Marcin Wróblewski, Marta Pawłowska, Roland Wesołowski, Joanna Wróblewska, Alina Woźniak   +6 more
doaj   +3 more sources

Exploring Novel Vitamin K Derivatives with Anti-SARS-CoV‑2 Activity

ACS Omega, 2023
From our compound library of vitamin K derivatives, we found that some compounds exhibited anti-SARS-CoV-2 activity in VeroE6/TMPRSS2 cells. The common structure of these compounds was menaquinone-2 (MK-2) with either the m-methylphenyl or the 1-naphthyl group introduced at the end of the side chain.
Taiki Homma, Mika Okamoto, Ryohto Koharazawa, Mayu Hayakawa, Taiki Fushimi, Chisato Tode, Yoshihisa Hirota, Naomi Osakabe, Masanori Baba, Yoshitomo Suhara   +9 more
doaj   +3 more sources

Vitamin K status and vascular calcification biomarkers as determinants of carotid plaque in peritoneal dialysis: a prospective study [PDF]

Renal Failure
Background Vitamin K deficiency impairs the activation of calcification inhibitors such as matrix Gla protein, promoting vascular calcification in CKD.
Irem Pamuk, Taha Enes Cetin, Beyza Hilal Kindan, Omer Faruk Akcay, Saliha Yildirim, Halit Nahit Sendur, Mahi Nur Cerit, Sevim Gonen, Burak Mert Akhan, Ulver Derici, Galip Guz, Ozant Helvaci   +11 more
doaj   +2 more sources

Decreased serum levels of 25-OH vitamin D and vitamin K in patients with type 2 diabetes mellitus

Frontiers in Endocrinology
BackgroundInsulin resistance and/or insulin secretion dysfunction are crucial causes of type 2 diabetes mellitus (T2DM). Although some studies have suggested potential roles for vitamins D and K in glucose metabolism and insulin sensitivity, there is ...
Ling Yang
doaj   +3 more sources

Effect of Vitamin K on Mothers and Neonates [PDF]

Minia Journal of Medical Research, 2022
Vitamin K was first discovered in the early 1930s by the Danish biochemist Henrik Dam who observed while studying cholesterol metabolism in chickens that chicks fed with a diet free of sterols and low in fat tended to develop subcutaneous and ...
Beshoy Asaad, Reem Abdel Aziz, Heba Hassan, Essa Mahmoud   +3 more
doaj   +1 more source

Prevalence of subclinical Vitamin K deficiency in early infancy in exclusively breast-fed term infants

Journal of Marine Medical Society, 2023
Background: Late Vitamin K deficiency bleeding, is a disease of exclusively breast-fed infants attributable to poor content of Vitamin K in breast milk.
Gitanjali Jain, K M Adhikari, Gautam Kumar Vasnik, Daljit Singh, Venkatesan Somasundaram, Rakesh Gupta, Puja Dudeja, Subhash Chandra Shaw   +7 more
doaj   +1 more source

Supplementary nutrients for prevention of vascular calcification in patients with chronic kidney disease [PDF]

The Korean Journal of Internal Medicine, 2019
Vascular calcification (VC) and malnutrition associated with cardiovascular disease are common in patients with chronic kidney disease (CKD) treated with dialysis.
Su Mi Lee, Won Suk An
doaj   +1 more source

Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH ₂ [PDF]

Proceedings of the National Academy of Sciences, 2006
More than 21 million prescriptions for warfarin are written yearly in the U.S. Despite its importance, warfarin's target, vitamin K epoxide reductase (VKOR), has resisted purification since its identification in 1972. Here, we report its purification and reconstitution.
Pei-Hsuan, Chu, Teng-Yi, Huang, Jason, Williams, D W, Stafford   +3 more
openaire   +2 more sources

The relationship between vitamin K and metabolic dysfunction-associated fatty liver disease among the United States population: National Health and Nutrition Examination Survey 2017–2018

Frontiers in Nutrition, 2023
BackgroundThe effect of vitamin K is associated with several pathological processes in fatty liver. However, the association between vitamin K levels and metabolic dysfunction-associated fatty liver disease (MAFLD) remains unclear.ObjectiveHere, we ...
Xinyue Wang, Wei Zhang, Jiale Huang, Hongwei Li, Jian Gao   +4 more
doaj   +1 more source

Symbiosis Mechanism of Associated Bacteria on 2-keto-L-gulonic Acid Production via Mixed Fermentation: A Review

Fermentation, 2023
Vitamin C, a water-soluble vitamin with strong reducing power, cannot be synthesized by the human body and participates in a variety of important biochemical reactions.
Wenhu Chen, Qian Liu, Meng Liu, Hongling Liu, Di Huang, Yi Jiang, Tengfei Wang, Haibo Yuan   +7 more
doaj   +1 more source