Results 151 to 160 of about 277,539 (261)

Lactate‐Induced K370 Lactylation of STING Inhibits STING‐TBK1 Signaling and Dampens Anti‐Tumor Immunity

Advanced Science, EarlyView.
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu, Jingzhe Wang, Xu Chen, Yuntong Yang, Ping Wei, Han Xie, Honghao Wang, Chunyu Zhang, Siyi Xu, Qi Wang, Chunlong Zhong, Jing Zhang   +11 more
wiley   +1 more source

Elevated Dietary Vitamin D Supplementation During Winter can Mimic Vitamin D Levels Induced by Summer Daylight Exposure in Atlantic Salmon. [PDF]

Aquac Nutr
Keitel-Gröner F, Knudsen DL, Hoel E, Sandstad M, Berge K.   +4 more
europepmc   +1 more source

Delay of Cucumber Senescence and Life‐Extending Capabilities on Caenorhabditis elegans With the Postharvest Application of Sorbitol and Methyl Salicylate

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Methyl salicylate and sorbitol were taken as coating agents. Caenorhabditis elegans was taken as an animal model. The coated agents were applied in C. elegans. The life span study in C. elegans proves the authenticity of MS and SL. MS and SL extended the post‐harvest life of cucumber for 14 days.
Chirayu H. Trivedi, Vajida Munshi, Kalpesh J. Mehta, Jitendriya Panigrahi   +3 more
wiley   +1 more source

Impact of trimester-specific nutrition counseling on maternal vitamin D status, and perinatal outcomes in India: a quasi-experimental cohort study. [PDF]

BMC Public Health
Khan MF, Al-Zharani M, Khurana A, Sharma KA, Nigam A, Alam S, Nasr FA, Qamar W, Idris MG, Rahman S, Dev K.   +10 more
europepmc   +1 more source

Improving the Physicochemical Properties, Organic Acids, Amino Acids, Volatile Organic Compounds, and Metabolites of Laohan Melon Juice Through Fermentation With Different Lactic Acid Bacteria

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermentation with lactic acid bacteria could improve amino acids, volatile organic compounds (VOCs), and nonvolatile metabolites of Laohan melon juice (LMJ), which provides theoretical guidance for the development of Laohan melon beverage and advances knowledge of the metabolic mechanisms of VOCs in LMJ.
Yun Xie, Sihan Hou, Mingdong Tan, Jianqiao Jiang, Yue Hu, Yiwen Chen, Yongkang Li, Miao Cui, Jianming Niu, Weidong Cheng, Xilei Pu, Yuyun He, Feifei Gao   +12 more
wiley   +1 more source

A randomized, open, two-period, cross-over, single oral dose, pharmacokinetics and bioequivalence study of vitamin K₁ in healthy volunteers under fasting and fed conditions. [PDF]

Front Pharmacol
Li Y, Wang Y, Qi L, Li Y, Zhong W, Wang X.   +5 more
europepmc   +1 more source

The Impacts of Health and Environmental Information Nudges on Meat Choices: Where Does Goat Meat Fit?

Agribusiness, EarlyView.
ABSTRACT Amidst a recent surge in US goat meat imports to meet growing demand, this study contributes to the meat demand literature by examining consumer preferences for goat meat, a relatively healthy and environmentally friendly alternative to other popular meats.
Binod Khanal, Sunil P. Dhoubhadel, Rodolfo M. Nayga Jr.   +2 more
wiley   +1 more source

Beyond 25(OH)D: Carboxylated Osteocalcin and the Undercarboxylated/Carboxylated Osteocalcin Ratio as Superior Biomarkers for Vitamin D Recovery in Offspring Affected by Maternal Deficiency. [PDF]

Nutrients
Chan WT, Lee HC, Yeung CY, Chiang Chiau JS, Cheng ML, Chang SW, Weng SC, Jiang CB.   +7 more
europepmc   +1 more source

Video and Text‐Based Supplemental Health Information and Consumer Willingness to Pay for Nutrient‐Enhanced Eggs

Agribusiness, EarlyView.
ABSTRACT Nutritional information is very important in the food choices of consumers. However, when they are too scientific or technical, they have the potential to confuse consumers, resulting in information asymmetry and dissuading them from making beneficial choices.
Edeoba W. Edobor, Michael J. Best, Anita R. Best, Ondulla T. Toomer   +3 more
wiley   +1 more source

Targeting the polyene chain represents an adjuvant strategy for optimizing polyene antifungals. [PDF]

Proc Natl Acad Sci U S A
Zhang Y, Liu X, Weng L, Li S, Chen P, Zhang G, Wang J, Zhang D, Tang C, Hu Y, Ye W, Zhang H.   +11 more
europepmc   +1 more source