Results 31 to 40 of about 10,028,727 (294)

Reply to. "inadequate anticoagulation by vitamin K antagonists and major adverse cardiovascular events other than stroke"

, 2016
Comment on Inadequate anticoagulation by Vitamin K Antagonists is associated with Major Adverse Cardiovascular Events in patients with atrial fibrillation. [Int J Cardiol.
PASTORI, DANIELE, PIGNATELLI, Pasquale, BARILLA', Francesco, Lip, Gregory Y. H, VICARIO, TOMMASA, SALIOLA, Mirella, VIOLI, Francesco, CARNEVALE, Roberto, CANGEMI, ROBERTO   +8 more
core   +1 more source

Treatment Strategies for Cryptogenic Stroke Patients with Patent Foramen Ovale: What Do We Choose?

Neuropsychiatric Disease and Treatment, 2021
Yu Shen,1,* Qiurui Nie,2,* Yibi Zhang,3 Qian Cao,1 Zhuo Hou,1 Lijun Xu1 1Department of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 2Department of Cardiovascular Medicine, People’
Shen Y, Nie Q, Zhang Y, Cao Q, Hou Z, Xu L   +5 more
doaj  

Massive Pulmonary Embolism in a Patient Using Warfarin at Therapeutic Dose [PDF]

Journal of Clinical and Diagnostic Research, 2016
Warfarin sodium is commonly used for the prevention and treatment of thromboembolism. The efficacy of warfarin therapy depends on maintaining the International Normalised Ratio (INR) within the target range for the indication.
Sunnetcioglu Aysel, Esen Ramazan, Arısoy Ahmet   +2 more
doaj   +1 more source

The Role of Vitamin K in Cirrhosis: Do Pharmaco-K-Netics Matter?

Gastrointestinal Disorders, 2022
Patients with advanced liver disease who are not taking vitamin K antagonists often have an elevated international normalized ratio, potentially due to vitamin K deficiency and the decreased synthesis of clotting factors by the liver. It is possible that
Stephanie Jin, Lisa Hong, Alireza FakhriRavari   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Assessing Safety of Direct Thrombin Inhibitors, Direct Factor Xa Inhibitors and Vitamin K Antagonists in Patients with Atrial Fibrillation: A Nation-Wide Propensity Score Matched Cohort from Sweden

Clinical Epidemiology, 2020
Marie Linder,1 Anastasia Iliadou Nyman,2,3 Helle Kieler,1 Bengt Danielsson,2 Natalia Borg,2 Marcus Gry,2 Julius Collin2 1Centre for Pharmacoepidemiology, Karolinska Institutet, T2, Karolinska University Hospital, Stockholm, Sweden; 2The National Board of
Linder M, Iliadou Nyman A, Kieler H, Danielsson B, Borg N, Gry M, Collin J   +6 more
doaj  

Vitamin K and childhood cancer: a report from the United Kingdom Childhood Cancer Study [PDF]

, 2003
The relationship between neonatal vitamin K received by the intramuscular (i.m.) route and the development of leukaemia or other cancers was investigated as part of a national case–control study of childhood cancer, using data abstracted from obstetric ...
Eden, O.B., Fear, NT, Day, N, Birch, Jillian, Fear, N. T., Simpson, J., Ansell, P, Fear, N.T., Simpson, J, Eden, O. B., E Roman, Roman, E., Roman, E, Ansell, P., N T Fear, N Day, O B Eden, ?, ?, Eden, OB, United Kingdom Childhood Cancer Study, Fear, N T, J Simpson, Eden, O B, Day, N., P Ansell   +24 more
core   +1 more source

Safety and efficacy of non-vitamin K antagonist oral anticoagulants for prevention of thromboembolism in adults with systemic right ventricle: Results from the NOTE international registry. [PDF]

, 2021
BACKGROUND Patients with systemic right ventricle (sRV), including transposition of great arteries (TGA) after atrial switch procedure and congenitally corrected transposition of great arteries (ccTGA), may require anticoagulation for thromboembolism (
Fernandes, Susan M, Egbe, Alexander C., Bouchardy, Judith, Broberg, Craig S., Schwerzmann, Markus, Aboulhosn, Jamil, Sarubbi, Berardo, Scognamiglio, Giancarlo, Tobler, Daniel, Budts, Werner, Lipczyńska, Magdalena, Fusco, Flavia, Fernandes, Susan M., Bouma, Berto J, Ladouceur, Magalie, Tsai, Shane F., Miranda, Berta, Rutz, Tobias, Dimopoulos, Konstantinos, Bouma, Berto J., Broberg, Craig S, Greutmann, Matthias, Niwa, Koichiro, Mizuno, Atsushi, Khairy, Paul, Tsai, Shane F, Alonso-Gonzalez, Rafael, Garr, BreAnn, Proietti, Anna, Hankel, Tara C., Mulder, Barbara J M, Mulder, Barbara J.M., Hankel, Tara C, Egbe, Alexander C, Egbe, A.C., Broberg CS, Rutz T, Aboulhosn, J., Greutmann, M., Bouma BJ, Scognamiglio G, Niwa, K., Ladouceur, M., Khairy P, Tobler D, Dimopoulos, K., Hankel, T.C., Bouma, B.J., Mulder BJM, Lipczyńska M, Scognamiglio, G., Alonso-Gonzalez, R., Broberg, C.S., Sarubbi B, Tobler, D., Fusco, F., Tsai SF, Ladouceur M, Garr, B., Niwa K, Lipczyńska, M., Tsai, S.F., Mulder, BJM, Schwerzmann M, Bouchardy J, Alonso-Gonzalez R, Fernandes, S.M., Proietti, A., Aboulhosn J, Rutz, T., Schwerzmann, M., Fernandes SM, Budts, W., Hankel TC, Mizuno A, Fusco F, Garr B, Khairy, P., Bouchardy, J., Sarubbi, B., Proietti A, Mizuno, A., Miranda, B., Greutmann M, Miranda B, Egbe AC, Dimopoulos K, Budts W   +87 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source