Results 81 to 90 of about 8,906,109 (167)

Effect of asciminib and vitamin K2 on Abelson tyrosine-kinase-inhibitor-resistant chronic myelogenous leukemia cells. [PDF]

BMC Cancer, 2023
Okabe S, Gotoh A.
europepmc   +1 more source

Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1) Gene Polymorphisms Predict Arterial Stiffness and Serum MGP Levels in Chronic Kidney Disease Patients. [PDF]

Genes (Basel)
Chen DH, Vermeer C, Cockcroft JR, Wheeler DC, O'Shaughnessy KM, Yasmin.   +5 more
europepmc   +1 more source

Leveraging Machine Learning to Predict Warfarin Sensitivity in the Puerto Rican Population: A Pharmacogenomic Approach. [PDF]

Int J Environ Res Public Health
Martínez-Jiménez JE, Ortega-Lampón Y, Cedres-Rivera D, Heredia-Negrón F, Roche-Lima A, Duconge J.   +5 more
europepmc   +1 more source

Predictor Role of <i>VKORC1</i> rs9923231, <i>CYP4F2</i> rs2108622, and <i>GGCX</i> rs11676382 Polymorphisms of 5 Years Mortality of Patients with Acute Ischemic Stroke. [PDF]

Medicina (Kaunas)
Iluţ S, Donca V, Macarie AE, Vesa ŞC, Pop RM, Văcăraş V, Şipoş-Lascu D, Bârsan IC, Perju-Dumbravă L, Chiroban OS, Coadă CA, Buzoianu AD.   +11 more
europepmc   +1 more source

The Genetic Polymorphisms of CYP2C9 and VKORC1 in the Saudi Population and Their Impact on Anticoagulant Management. [PDF]

Medicina (Kaunas)
Al Hamad M.
europepmc   +1 more source

Study of the Vitamin K Cyclic Metabolism in absence and presence of coumarin anticoagulants by Liquid Chromatography- Linear Ion Trap Mass Spectrometry

, 2011
In mammalians the only known function of vitamin K is that of γ-glutamylcarboxylase cofactor, enzyme catalyzing the posttranslational carboxylation of the so-called vitamin K-depending proteins.
PERRET, Daniela, C. VIGILANTE, CAFOLLA, Arturo, GENTILI, Alessandra, D'ASCENZO, Giuseppe   +4 more
core  

Explainable Artificial Intelligence Unravels the Possible Distinct Roles of VKORC1 and CYP2C9 in Predicting Warfarin Anticoagulation Control. [PDF]

Med Sci (Basel)
Sridharan K, Sivaramakrishnan G.
europepmc   +1 more source

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans. [PDF]

Clin Pharmacol Ther
Chen S, Chen H, Xu S.
europepmc   +1 more source

Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism. [PDF]

Cell Metab, 2023
Yang X, Wang Z, Zandkarimi F, Liu Y, Duan S, Li Z, Kon N, Zhang Z, Jiang X, Stockwell BR, Gu W.   +10 more
europepmc   +1 more source

Improving Genotype Imputation in High-Dimensional Pharmacogenomics Using Multiple Imputation: Evaluation with Machine Learning Approaches. [PDF]

Clin Pharmacol Ther
Asiimwe IG, You T, Carr DF, Pirmohamed M, Davies G, Jorgensen AL, UNITE4TB Consortium.   +6 more
europepmc   +1 more source