Results 181 to 190 of about 832,047 (339)

Combined effects of vitamin D and neferine on the progression and metastasis of colorectal cancer [PDF]

, 2023
Jinfeng Yang, Qinyu Zhang, Guanlin Huang, Jiacheng Cong, Ting Wang, Xiaoya Zhai, Juzheng Zhang, Guangying Qi, Lihua Zhou, Jiamin Jin   +9 more
openalex   +1 more source

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

The relationship between dietary intake of B vitamins and H. pylori seropositivity. [PDF]

PLoS One
Lu Y, Wang T, Yuan S, Ouyang J, Dong J, Jiang X, Shao X, Xu H, Zhang R.   +8 more
europepmc   +1 more source

Association of pre-eclampsia risk with maternal levels of folate, homocysteine and vitamin B12 in Colombia: A case-control study

, 2018
Norma C. Serrano, Doris Cristina Quintero-Lesmes, Silvia Becerra‐Bayona, Elizabeth Guío, Mónica Beltrán, María Carolina Páez, Ricardo Ortiz, Wilmar Saldarriaga, Luis Alfonso Díaz‐Martínez, Álvaro Monterrosa, Jezid Miranda, Clara M. Mesa, Jose Enrique Sanín, Germán Monsalve, Frank Dudbridge, Aroon D. Hingorani, Juan P. Casas   +16 more
openalex   +2 more sources

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

Advanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu, Weixia Xuan, Song Cao, Huayun Jia, Qian Wu, Xiaowu Tan, Qijie Wang, Xiaojun Li, Lisha Ding, Yaru Xiong, Meiyun Zhao, Longcheng Zheng, Yunzhu Xi, Jianhua Tan, Rong Li, Xulong Zhang, Wenjie Liu, Xu Wu   +17 more
wiley   +1 more source

Vitamins in the Treatment of Periodontitis: Molecular Mechanism and Network Pharmacological Analysis. [PDF]

Oral Health Prev Dent
Wang LR, Liu DX, Yu L, Gao L.
europepmc   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Associations Between Single and Multiple Vitamins and the Risk of Dental Caries: Results from a Cross-Sectional Study and Mendelian Randomisation Analysis. [PDF]

Oral Health Prev Dent
He Q, Xu H, Liu M, Yu Q, Lin M.
europepmc   +1 more source