Results 191 to 200 of about 737,693 (384)

Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia‐Induced Vascular Injury

open access: yesAdvanced Science, EarlyView.
Mitophagy switching drives high‐glucose‐induced vascular endothelial injury. Short‐term high‐glucose exposure upregulates Fis1 expression and enhances Fis1‐TBC1D15 interaction, activating Parkin‐mediated mitophagy. Long‐term high‐glucose exposure reduces Fis1 expression, inhibiting Parkin‐mediated mitophagy and triggering mitophagy switching from ...
Anqi Luo   +10 more
wiley   +1 more source

FAT-SOLUBLE VITAMINS

open access: hybrid, 1925
H. Steenbock   +4 more
openalex   +1 more source

Cobalt Single‐Atom Intercalation in Molybdenum Disulfide Enhances Piezocatalytic and Enzyodynamic Activities for Advanced Cancer Therapeutics

open access: yesAdvanced Science, EarlyView.
The single‐atom doped molybdenum disulfide piezocatalyst markedly enhances both piezoelectric and enzyme‐mimicking activities, accelerating glutathione depletion. It induces mitochondrial dysfunction and cell cycle arrest, ultimately driving apoptosis while inactivating glutathione peroxidase 4 to initiate ferroptosis.
Haomiao Bai   +8 more
wiley   +1 more source

Homocysteine Promotes the Pathogenesis of Atherosclerosis through the Circ‐PIAS1‐5/miR‐219a‐2‐3p/TEAD1 Axis

open access: yesAdvanced Science, EarlyView.
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma   +13 more
wiley   +1 more source

A Model Checker for Natural Strategic Ability [PDF]

open access: yesarXiv
In the last two decades, Alternating-time Temporal Logic (ATL) has been proved to be very useful in modeling strategic reasoning for Multi-Agent Systems (MAS). However, this logic struggles to capture the bounded rationality inherent in human decision-making processes.
arxiv  

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