Omega-3 supplementation in addition to prenatal vitamins during pregnancy is associated with lower rates of preterm birth and small for gestational age. [PDF]
Yakah W +9 more
europepmc +1 more source
Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han +9 more
wiley +1 more source
Vitamins in the Treatment of Periodontitis: Molecular Mechanism and Network Pharmacological Analysis. [PDF]
Wang LR, Liu DX, Yu L, Gao L.
europepmc +1 more source
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang +7 more
wiley +1 more source
Effects of Vitamin C and/or E Supplementation on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes: A Systematic Review and Subgroup Meta-analysis. [PDF]
Aragón-Vela J, Huertas JR, Casuso RA.
europepmc +1 more source
ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao +19 more
wiley +1 more source
Dietary B-complex vitamins and sleep quality in relation to cognitive impairment among older adults: non-linear associations and evidence of additive interaction. [PDF]
Zhang M +7 more
europepmc +1 more source

