Results 61 to 70 of about 74,162 (293)

Retention of Pro-Vitamin A Content in Products from New Biofortified Cassava Varieties [PDF]

Foods, 2019
Plant breeding efforts in sub-Saharan Africa (SSA) have produced biofortified cassava with high carotenoid content to address vitamin A deficiencies (VAD). Since carotenoids in foods are easily depleted during processing, the retention of β-carotene in some newly released cassava varieties is under query.
Toluwalope Emmanuel Eyinla, Busie Maziya-Dixon, Oladeji Emmanuel Alamu, Rasaki Ajani Sanusi   +3 more
openaire   +4 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

doi: http://dx.doi.org/10.15407/ubj86.04.138 [PDF]

The Ukrainian Biochemical Journal, 2014
Connective tissue is highly susceptible to imbalances induced by diabetes. Diabetes-related osteopenia, decreased bone strength etc. may be associated with altered metabolism of various collagens. Although it is assumed that alterations in collagen amino
M. M. Guzyk, Iu. T. Sergiichuk, K. O. Dyakun, L. V. Yanitska, T. M. Kuchmerovska   +4 more
doaj   +1 more source

Effect of Tamarillo Fortification and Fermentation Process on Physicochemical Properties and Nutrient and Volatiles Content of Yoghurt

Foods, 2021
Bright-red Laird’s Large tamarillo is a unique and under-utilised fruit that is a dietary source of carotenoids, vitamins C and E, and dietary fibre. The effects of the addition of freeze-dried tamarillo powder (5–15%) to milk and yoghurt starter either ...
Tung Thanh Diep, Michelle Ji Yeon Yoo, Elaine Rush   +2 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Biochemical and haematological changes in peripheral blood of rats exposed to chlorpyrifos: protective effect of vitamins A and E combination

Біологічні студії, 2015
Chlorpyrifos is a highly toxic organophosphate compound. It is still among the most widely used insecticide, and the main mechanism of its toxicity is associated with inhibition of cholinesterases.
V. P. Rosalovsky, S. V. Grabovska, Yu. T. Salyha   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Assessment of the feed additive consisting of calcium D‐pantothenate for all animal species for the renewal of its authorisation (BASF SE)

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of calcium D‐pantothenate for the renewal of its authorisation as a nutritional feed additive for all animal species. The additive
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Jaume Galobart, Orsolya Holczknecht, Fabiola Pizzo, Maria Vittoria Vettori, Anita Radovnikovic   +21 more
doaj   +1 more source

The Importance of Micronutrient Adequacy in Obesity and the Potential of Microbiota Interventions to Support It

Applied Sciences
Micronutrient deficiencies co-occur with obesity throughout the world. While many factors may contribute to this, microbiota dysbiosis is certainly one that has received a lot of attention in recent years.
Agnieszka Rudzka, Kamila Kapusniak, Dorota Zielińska, Danuta Kołożyn-Krajewska, Janusz Kapusniak, Renata Barczyńska-Felusiak   +5 more
doaj   +1 more source