Results 71 to 80 of about 203,213 (324)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Beyond deficiency:Potential benefits of increased intakesof vitamin K for bone and vascular health [PDF]

, 2004
Vitamin K is wellknown for its role in the synthesisof a number of blood coagulationfactors.During recent years vitaminK-dependent proteins werediscovered to be of vital importancefor bone and vascular health.Recommendations for dietary vitaminK intake ...
Bolton-Smith, C, Hodges, S, Rambeck, W, Shearer, M, Stocklin, E, Szulc, P, Vermeer, C, Walter, P, Weber, P, Zittermann, A   +9 more
core  

Regulation of the microecological state of the lower parts of the female reproductive tract with vitamins

Журнал микробиологии, эпидемиологии и иммунобиологии, 2020
Aim. To study the changes in the microecology of the vagina under the influence of ascorbic acid, α-tocopherol, and retinol acetate.Materials and methods.
Olga A. Strokova, Elena A. Kremleva, Olga D. Konstantinova, Andrey V. Sgibnev   +3 more
doaj   +1 more source

Analysis of biopharma raw materials by electrophoresis microchips with contactless conductivity detection [PDF]

, 2009
Detailed information concerning the composition of the raw materials employed in the production of biologics is important for the efficient control and optimization of bioprocesses.
Benito-Lopez, Fernando, Diamond, Dermot, Garcia-Cordero, Jose L., Ricco, Antonio J., Vázquez, Mercedes   +4 more
core  

Toward eradication of B-vitamin deficiencies : considerations for crop biofortification [PDF]

, 2018
'Hidden hunger' involves insufficient intake of micronutrients and is estimated to affect over two billion people on a global scale. Malnutrition of vitamins and minerals is known to cause an alarming number of casualties, even in the developed world ...
Strobbe, Simon, Van Der Straeten, Dominique   +1 more
core   +3 more sources

Anti-adipogenic and Pro-osteoblastogenic Activities of Spergularia marina Extract

Preventive Nutrition and Food Science, 2014
For decades, Spergularia marina, a local food that is popular in South Korea, has been regarded as a nutritious source of amino acids, vitamins, and minerals. While several halophytes are reported to possess distinct bioactivities, S.
F. Karadeniz, Jung-Ae Kim, Byul‐Nim Ahn, Mihyang Kim, C. Kong   +4 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Boosting pro-vitamin A content and bioaccessibility in leaves by combining engineered biosynthesis and storage pathways with high-light treatments

The Plant Journal, 2023
SUMMARYThe relevance of plants as food is expected to grow for a more sustainable diet. In this new context, improving the nutritional quality of plant-derived foods is a must. Biofortification of green leafy vegetables with pro-vitamin A carotenoids such as β-carotene has remained challenging to date.
Luca Morelli, Pablo Perez‐Colao, Diego Reig‐Lopez, Xueni Di, Briardo Llorente, Manuel Rodriguez‐Concepcion   +5 more
openaire   +3 more sources

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Physico-Chemical Quality of Processed Nutrient-Dense Garri (NDG) from Pro-Vitamin A Cassava and Soybean

European Journal of Food Science and Technology, 2023
Garri is a popular and commonly consumed staple food in Nigeria especially among the Eastern and Southern Nigerians. It is nutritionally inadequate with main nutrient as carbohydrate. We examined the potential of yellow cassava fortification with soybean in the production of Nutrient dense garri (NDG) to improve nutrient quality of garri.
E. O Farinde, V. A. Obatolu, B. N. Ezugwu, T. O Dauda, O. M Taiwo   +4 more
openaire   +1 more source