Results 11 to 20 of about 60,298 (290)

A case of hyperpigmentation induced by hydroxychloroquine and quinacrine in a patient with systemic lupus erythematosus and review of the literature

International Journal of Women's Dermatology, 2020
Hydroxychloroquine (HQ) and quinacrine are widely used antimalarials for systemic lupus erythematosus (SLE) and other autoimmune diseases. We report a case of antimalarial-induced hyperpigmentation in a 57-year old African-American woman. The patient had
Daniel Kwak, Pearl E. Grimes, MD
doaj   +1 more source

From zero to one: Recent advances in the pathogenesis, diagnosis, and treatment of vitiligo

Dermatologica Sinica, 2023
Vitiligo is the most common acquired pigmentary disorder and can have profound negative psychosocial impacts on patients. The disease course of vitiligo is often unpredictable, and diagnosis and treatment of vitiligo remain a challenging dermatological ...
Peng-Chieh Shen, Tsung-Fu Tsai, Yi-Jing Lai, Tzu-Li Liu, Chau Yee Ng   +4 more
doaj   +1 more source

A survey study of self‐reported comorbidities among adults with vitiligo in the United States

JEADV Clinical Practice, 2023
Background Vitiligo is an autoimmune disorder in which the immune system targets melanocytes, manifesting in patches of lost skin pigmentation. Objectives To characterize the occurrence of autoimmune/autoinflammatory and/or nonautoimmune comorbid ...
Khaled Ezzedine, Kathryn P. Anastassopoulos, Kavita Gandhi, Shoshana R. Daniel, Yuji Yamaguchi, Vanja Sikirica, Amit G. Pandya   +6 more
doaj   +1 more source

The Difference in Expression of Autophagy-Related Proteins in Lesional and Perilesional Skin in Adult Patients with Active and Stable Generalized Vitiligo—A Cross-Sectional Pilot Study

Indian Journal of Dermatology, 2021
Background: Autophagy plays an important role in maintaining intracellular homeostasis and is essential for cell survival and cell death. Dysfunction of autophagy has been described in many autoimmune diseases but data on vitiligo are scarce.
Haiyan Yu, Xiaoxia Lin, Yaoyao Huang, Hao Cheng, Oliver Seifert   +4 more
doaj   +1 more source

The relationship between stress and vitiligo: Evaluating perceived stress and electronic medical record data. [PDF]

PLoS ONE, 2020
Vitiligo is a T-cell mediated skin disorder characterized by progressive loss of skin color. In individuals genetically predisposed to the disease, various triggers contribute to the initiation of vitiligo.
Steven W Henning, Dinesh Jaishankar, Levi W Barse, Emilia R Dellacecca, Nicola Lancki, Kirsten Webb, Linda Janusek, Herbert L Mathews, Ronald N Price, I Caroline Le Poole   +9 more
doaj   +1 more source

Innate immune activation in vitiligo: mechanisms and pathophysiological implications. [PDF]

Front Immunol
Vitiligo is an autoimmune disease characterized by the progressive destruction of epidermal melanocytes, leading to skin depigmentation. Although significant advances have been made in understanding the pathogenesis of vitiligo, the intricate interplay ...
Wang Y, Cao J, Liu X, Xiong C, Xu D, Bian F.   +5 more
europepmc   +2 more sources

New oral and topical approaches for the treatment of melasma

International Journal of Women's Dermatology, 2019
Melasma is a common, therapeutically challenging, and universally relapsing disorder of hyperpigmentation that is most often observed in women and individuals with Fitzpatrick Skin Types III through VI. The pathogenesis of melasma is complex and protean.
P.E. Grimes, MD, S. Ijaz, BA, MPH, R. Nashawati, BS, MSGM, D. Kwak   +3 more
doaj   +1 more source

Disease stability in segmental and non-segmental vitiligo

Indian Dermatology Online Journal, 2022
Introduction: Some therapeutic decisions in vitiligo depend on the likelihood of the disease remaining stable and inactive. Aim: To determine a period of disease stability in vitiligo following which reactivation was unlikely. Materials and Methods: This
Neha Taneja, V Sreenivas, Kanika Sahni, Vishal Gupta, M Ramam   +4 more
doaj   +1 more source

Knowledge, attitudes and practices of the general public toward sun exposure and protection: A national survey in

Saudi Pharmaceutical Journal, 2016
Background: Many international studies have been conducted to assess the knowledge, attitudes and practices (KAP) of the public toward sun exposure and sun-protection measures.
Khalid M. AlGhamdi, Aeed S. AlAklabi, Abdulla Z. AlQahtani   +2 more
doaj   +1 more source

Does the Saudi Population Have Sufficient Awareness of Vitiligo in Southwest Saudi Arabia? A Cross-Sectional Survey, 2022

Clinics and Practice, 2022
Background: Vitiligo is a common acquired hypopigmentation skin condition defined by an idiopathic, gradual, and restricted loss of melanin pigment from otherwise healthy-looking skin.
Fatmah Ahmed Keraryi, Alhanouf Adel Hadi Hakami, Nouf Adel Hadi Hakami, Mohamed Salih Mahfouz, Hadi Adel Hadi Hakami   +4 more
doaj   +1 more source