Results 41 to 50 of about 60,298 (290)

Serum thyroid hormone antibodies are frequent in patients with polyglandular autoimmune syndrome type 3, particularly in those who require thyroxine treatment [PDF]

, 2017
Polyglandular autoimmune syndrome (PAS) type 3 consists of autoimmune thyroid disease (AITD) coexisting with ≥1 non-thyroidal autoimmune disease (NTAID) other than Addison’s disease and hypoparathyroidism. We evaluated the prevalence and repertoire of
Benvenga, Salvatore, Centanni, Marco, Di Bari, Flavia, Galletti, Marina, Mandolfino, Mattia, Santaguida, MARIA GIULIA, Segni, Maria, Virili, Camilla, Vita, Roberto   +8 more
core   +1 more source

A cross-sectional study of the levels of cytokines IL-6, TNF-α, and IFN-γ in blood and skin (lesional and uninvolved) of vitiligo patients and their possible role as biomarkers

Indian Journal of Dermatology, 2023
Introduction: Vitiligo is a multifactorial disorder, most often explained by the autoimmune hypothesis. The objective of this study is to measure the levels of cytokines IL-6, TNF-α, and IFN-γ in the blood and skin (lesional and uninvolved) of vitiligo ...
Abhishek De, Nidhi Choudhary, Amrita Sil, Aarti Sarda, Abu Hena Hasanoor Raja   +4 more
doaj   +1 more source

Frontiers in Pigment Cell and Melanoma Research

, 2018
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current ...
Birlea, Stanca, Bosenberg, Marcus W., Box, Neil F., Brash, Douglas, Cassidy, Pamela B., Chen, Suzie, D'Orazio, John August, Filipp, Fabian V., Fujita, Mayumi, Goh, Boon-Kee, Herlyn, Meenhard, Indra, Arup K., Larue, Lionel, Leachman, Sancy A., Liu-Smith, Feng, Manga, Prashiela, Montoliu, Lluis, Norris, David A., Poole, Caroline Le, Shellman, Yiqun, Smalley, Keiran S. M., Spritz, Richard A., Sturm, Richard A., Swetter, Susan M., Terzian, Tamara, Wakamatsu, Kazumasa, Weber, Jeffrey S.   +26 more
core   +1 more source

Survey and online discussion groups to develop a patient-rated outcome measure on acceptability of treatment response in vitiligo [PDF]

, 2014
BackgroundVitiligo is a chronic depigmenting skin disorder which affects around 0.5-1% of the world’s population. The outcome measures used most commonly in trials to judge treatment success focus on repigmentation.
Batchelor, Jonathan M., Leighton, Paul, Thomas, Kim S., Tour, Selina K., Walker, Dawn-Marie, Yong, Adrian S.W.   +5 more
core   +2 more sources

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Mental Health and Psychosocial Burden Among Patients with Skin of Color Living with Vitiligo: Findings from the Global VALIANT Study

Dermatology and Therapy
Introduction Factors associated with vitiligo burden in patients with darker skin (Fitzpatrick skin types IV–VI) are not fully understood. This analysis of patients in the global VALIANT study examined the quality of life (QoL) and psychosocial health ...
Pearl Grimes, Iltefat H. Hamzavi, Kristen Bibeau, John E. Harris, Nanja van Geel, Davinder Parsad, Jackie Gardner, Yan Valle, Gaone Tlhong Matewa, Jessy Gao, Haobo Ren, Khaled Ezzedine   +11 more
doaj   +1 more source

Tribulus terrestris L.: a medicinal plant with promising therapeutic potential for skin diseases

Frontiers in Pharmacology
Tribulus terrestris L. (T. terrestris L.), a traditional medicinal plant, has garnered increasing attention for its potential in treating skin disease. This review comprehensively summarizes current research on the protective effects of T.
Xiao-Mu Wang, Xiao-Min Liu, Yan Zeng, Ke-Jing Zhu, Tian-Tian Shen, Fang Bian   +5 more
doaj   +1 more source

Clinical characteristics of late-onset vitiligo in an Iranian population

Dermatologica Sinica, 2012
Background: The age of onset of vitiligo is before 20 years in approximately in 50% of patients, and its incidence decreases with increasing age. In this study, our aim was to analyze the epidemiological and clinical factors of patients with late-onset ...
Iraj Esfandiarpour, Saeedeh Farajzadeh
doaj   +1 more source

Metabolomics Signature and Potential Application of Serum Polyunsaturated Fatty Acids Metabolism in Patients With Vitiligo

Frontiers in Immunology, 2022
Vitiligo is a depigmented skin disorder caused by a variety of factors, including autoimmune, metabolic disturbance or their combined effect, etc.
Zhubiao Ye, Jianru Chen, Pengran Du, Qingrong Ni, Baizhang Li, Zhe Zhang, Qi Wang, Tingting Cui, Xiuli Yi, Chunying Li, Shuli Li   +10 more
doaj   +1 more source

Determining the Characteristic Vocabulary for a Specialized Dictionary using Word2vec and a Directed Crawler [PDF]

, 2016
Specialized dictionaries are used to understand concepts in specific domains, especially where those concepts are not part of the general vocabulary, or having meanings that differ from ordinary languages.
Grefenstette, Gregory, Muchemi, Lawrence
core   +3 more sources