Results 51 to 60 of about 13,415 (150)

Mind the GAPS: Glia associated with psychological stress

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Glial cells are an integral component of the nervous system, performing crucial functions that extend beyond structural support, including modulation of the immune system, tissue repair, and maintaining tissue homeostasis. Recent studies have highlighted the importance of glial cells as key mediators of stress responses across different organs.
Niklas Blank   +4 more
wiley   +1 more source

Clonal hematopoiesis of indeterminate potential and the risk of autoimmune diseases

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background Clonal hematopoiesis of indeterminate potential (CHIP), characterized by the age‐related expansion of blood cells carrying preleukemic mutations, is associated with immune aging. This study aimed to investigate the association between CHIP and established autoimmune diseases. Methods We analyzed baseline data from 456,692 UK Biobank
Hanzhang Wu   +4 more
wiley   +1 more source

A Phase 1, Open‐Label Study of the Pharmacokinetics of Ritlecitinib in Children Aged 6–12 Years With Alopecia Areata

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Background Alopecia areata (AA) is an autoimmune disease characterized by hair loss that can negatively impact quality of life. AA has a significant pediatric prevalence; however, no systemic treatments are approved for AA in patients aged < 12 years. Ritlecitinib, a JAK3/TEC family kinase inhibitor, is approved to treat adults and adolescents
Mercedes E. Gonzalez   +7 more
wiley   +1 more source

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