Results 51 to 60 of about 57,061 (258)

Clinico-epidemiological profile of vitiligo patients in Najran Region, Saudi Arabia

Journal of Dermatology and Dermatologic Surgery, 2015
Objectives: To assess the prevalence of vitiligo among patients with dermatological diseases in Najran, South-Western Saudi Arabia, and to explore the epidemiological profile of vitiligo patients in the region. Materials and methods: This single-observer,
Hamad Ayed AL Fahaad
doaj   +1 more source

Frontiers in Pigment Cell and Melanoma Research

, 2018
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current ...
Birlea, Stanca, Bosenberg, Marcus W., Box, Neil F., Brash, Douglas, Cassidy, Pamela B., Chen, Suzie, D'Orazio, John August, Filipp, Fabian V., Fujita, Mayumi, Goh, Boon-Kee, Herlyn, Meenhard, Indra, Arup K., Larue, Lionel, Leachman, Sancy A., Liu-Smith, Feng, Manga, Prashiela, Montoliu, Lluis, Norris, David A., Poole, Caroline Le, Shellman, Yiqun, Smalley, Keiran S. M., Spritz, Richard A., Sturm, Richard A., Swetter, Susan M., Terzian, Tamara, Wakamatsu, Kazumasa, Weber, Jeffrey S.   +26 more
core   +1 more source

Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis [PDF]

, 2009
Targeted immune-modulating agents are entering clinical practice in many specialties, providing novel therapeutic possibilities but introducing new potential toxicities.
Clatworthy, Menna R, Farrington, Ken, Jolly, Elaine C, Lawrence, Christopher, Nathan, Paul D   +4 more
core   +2 more sources

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

Advanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li, Xinzhu Li, Xiao Xiang, Jundong Huang, Xinyu Shen, Mengyue Wang, Jingwei Jiang, Shiwen Shao, Zeming Li, Tian Xie, Deming Liu, Yiping Zhao, Rui Ma, Wenyu Wu, Wei Shi, Cheng‐Ming Chuong, Ji Li, Mingxing Lei   +17 more
wiley   +1 more source

MicroRNA-146a and Forkhead box protein 3 expressions in nonsegmental vitiligo: an insight into disease pathogenesis

Journal of the Egyptian Women’s Dermatologic Society, 2019
Background Autoimmune destruction of melanocytes is the principal hypothesis in vitiligo pathogenesis. MicroRNA-146a (miRNA-146a) is considered an essential regulator of posttranscriptional gene expression, suggesting a potential role in autoimmune ...
Arwa M Hassan, Yomna M. El-Hamd Neinaa, Amal S El-Bendary, Soha S Zakaria   +3 more
doaj   +1 more source

Public knowledge and attitude toward vitiligo in Saudi Arabia: A cross-sectional study

Journal of Dermatology and Dermatologic Surgery, 2021
Background: Knowledge and positive attitude toward vitiligo would foster support for affected individuals, improving their sense of well-being and possibly treatment outcome.
Malak A M Algarni, Waleed A Alqarni, Logain G Alghanemi, Maryam M Alnashri, Rand G Alghanemi, Nouf T Mleeh   +5 more
doaj   +1 more source

Computerised image analysis of vitiligo lesion: evaluation using manually defined lesion areas [PDF]

, 2013
Background: Vitiligo is a cutaneous pigmentary disorder characterized by depigmented macules and patches that result from loss of epidermal melanocytes. Physician evaluates the efficacy of treatment by comparing the extent of vitiligo lesions before and ...
Hussein, Suraiya Hani, Mohd Hani, Ahmad Fadzil, Nugroho, Hermawan, Shamsudin, Norashikin   +3 more
core   +1 more source

A Transcriptome‐Wide Mendelian Randomization Study in Isolated Human Immune Cells Highlights Risk Genes Involved in Viral Infections and Potential Drug Repurposing Opportunities for Schizophrenia

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey, Liam Gaziano, Preethi Eldi, Catherine Toben, Beben Benyamin, S. Hong Lee, Elina Hyppönen   +6 more
wiley   +1 more source

Insight into Natural History of Congenital Vitiligo: A Case Report of a 23-Year-Old with Stable Congenital Vitiligo

Case Reports in Dermatological Medicine, 2017
Vitiligo is a disorder of skin pigmentation. It affects approximately 1% of the world’s population. Vitiligo occurs equally between the sexes with no racial predilections.
Chelsea Casey, Stephen E. Weis
doaj   +1 more source

The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. [PDF]

, 2016
BackgroundPUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of ...
Abrouk, Michael, Bhutani, Tina, DaLovisio, Renee, Farahnik, Benjamin, Jose, Margareth V, Koo, John, Lee, Kristina M, Liao, Wilson, Nakamura, Mio, Singh, Rasnik K, Zhu, Tian Hao   +10 more
core   +3 more sources