Results 41 to 50 of about 98,722 (263)

Complement inhibitor therapy in atypical hemolytic uremic syndrome (aHUS): evaluating the economic impact of introducing eculizumab biosimilars in Germany

BMC Nephrology
Background Eculizumab, a humanized monoclonal antibody, inhibits activation of complement component C5. For patients with atypical hemolytic uremic syndrome, the introduction of eculizumab has markedly improved survival, restoring life expectancy close ...
Isabell Kaufhold, Daniel Lewkowicz, Danila Seidel, Paul Thomas Brinkkoetter, Florian Kron   +4 more
doaj   +1 more source

Immuntherapien beim nicht-kleinzelligen Lungenkarzinom zwischen Innovation und Wirtschaftlichkeit

Monitor Versorgungsforschung
Einleitung: Das nicht-kleinzellige Lungenkarzinom (NSCLC) ist die häufigste Form des Lungenkarzinoms. Immuncheckpoint-Inhibitoren haben die Therapie in den letzten Jahren grundlegend verändert, sind jedoch mit hohen Arzneimittelkosten verbunden.
Katja Heße MSc, Jasmin Nachtigall MSc, Johanna Röder MSc   +2 more
doaj   +1 more source

A chemotaxonomic investigation on Vitis vinifera L. 3. Characterization of Vitis biotypes via root apex proteins [PDF]

, 2015
Soluble proteins from root tips were used as biochemical markers to study, taxonomically and systematically, Vitis biotypes. Analyses of total proteins in the pH range 3.5-10 and of the enzymes AcP, ADH, EST, PGM and POD indicate that only in the case of
Villa, P., Scienza, A., Tedesco, G., Valenti, L., Sala, Elena   +4 more
core   +1 more source

Advancing SafeWax, A Bio‐Inspired Superhydrophobic Coating, Toward Sustainable and Climate‐Resilient Crop Protection

Advanced Functional Materials, EarlyView.
This study advances SafeWax, a bio‐inspired, fatty‐acids‐based superhydrophobic coating, by identifying an agriculturally compliant solvent and revealing how solvent‐controlled Fatty acid crystallization governs the coating's microscopic structure and performance.
Niv Ben‐Arie, Iryna Polishchuk, Franziska Tauber, Coralie Schneider, Elena Prudnikov, Alessia Calora, Silvia Milita, Simona Fermani, Mireia Alejandra Ibanez Revert, Ilaria Filippetti, Claudio Ratti, Matthias Kellermeier, Markus Rueckel, Boaz Pokroy   +13 more
wiley   +1 more source

Cost-effectiveness analysis of molecular reflex testing-based targeted therapy in non-small cell lung cancer from a German healthcare payer perspective using a decision tree model

Cost Effectiveness and Resource Allocation
Background Reflex testing (RT) - pathologist-initiated molecular testing performed at non–small cell lung cancer (NSCLC) diagnosis - enables rapid identification of actionable genomic alterations for targeted therapy (TT) selection.
Leonie Schumacher, Melina Sophie Kurte, Tabea Poos, Markus Thalheimer, Frank Griesinger, Florian Kron   +5 more
doaj   +1 more source

Effects of preharvest application of TH 6241 and CEPA on Vitis vinifera [PDF]

, 2017
Mature vines of the Vitis vinifera cultivars Thompson Seedless, Barbera, Cabernet-Sauvignon, Ruby Cabernet, and Alphonse Lavallee were treated with TH 6241 and CEPA at various concentrations.
Eynard, I.
core   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source

Innovative Antimykotika-Therapie und Versorgungssteuerung entlang der transsektoralen Patient-Journey

Monitor Versorgungsforschung
Invasive Pilzinfektionen wie Candidämie und invasive Candidiasis erfordern häufig langwierige stationäre Behandlungen aufgrund des kontinuierlichen Therapiebedarfs und gehen mit hohen Sterblichkeitsraten einher.
Prof. Dr. rer. medic. Florian Kron, Johanna Röder MSc, Katja Heße MSc, Dr. rer. medic. Sebastian Wingen-Heimann, Prof. Dr. rer. pol. Björn Maier, Dr. rer. nat. Nils Keiner, Prof. Dr. med. Oliver Cornely   +6 more
doaj   +1 more source

Genska banka Fakultete za kmetijstvo in biosistemske vede (FKBV) Univerze v Maribor

Acta Agriculturae Slovenica, 2012
Gensko banko Fakultete za kmetijstvo in biosistemske vede (FKBV) smo začeli oblikovati leta 1996. Prvih 10 let je delo potekalo na zbiranju in vzdrževanju rastlinskih genskih virov in je bilo prilagojeno predvsem pedagoškim potrebam fakultete in ...
Metka ŠIŠKO, Anton IVANČIČ
doaj   +1 more source

Pollen dimorphism and dioecy in Vitis aestivalis [PDF]

, 2015
Problems of low production and sterile pollen in varieties of Vitis vinifera may be tracable to their ancestral relations with dioecious wild grapes.Like V. riparia, the wild summer grape V. aestivalis has dimorphic male and female flowers; but unlike V.
Kevan, P. G., Posluszny, U., Blades, D. C. A., Ambrose, J. D.   +3 more
core   +1 more source