Osteoprotegerin is a new regulator of inflammation and angiogenesis in proliferative diabetic retinopathy [PDF]
Osteoprotegerin (OPG) is a novel regulator of endothelial cell function, angiogenesis, and vasculogenesis. We correlated expression levels of OPG with those of the angiogenic and inflammatory factors vascular endothelial growth factor (VEGF) and monocyte
Abu El-Asrar, Ahmed M +11 more
core +3 more sources
Salinomycin inhibits proliferative vitreoretinopathy formation in a mouse model.
Proliferative vitreoretinopathy (PVR) is a progressive disease that develops in a subset of patients who undergo surgery for retinal detachment repair, and results in significant vision loss.
Alison M Heffer +5 more
doaj +1 more source
Personalized Medicine in Ocular Fibrosis: Myth or Future Biomarkers [PDF]
SIGNIFICANCE: Fibrosis-related events play a part in the pathogenesis or failure of treatment of virtually all the blinding diseases around the world, and also account for over 40% of all deaths.
Khaw, PT, Yu-Wai-Man, C
core +1 more source
Therapeutic Interventions against Inflammatory and Angiogenic Mediators in Proliferative Diabetic Retinopathy [PDF]
The global prevalence of diabetes is estimated to be 336 million people, with diabetic complications contributing to significant worldwide morbidity and mortality.
Gologorsky, Daniel +2 more
core +3 more sources
Hybrid wide-angle viewing-endoscopic vitrectomy using a 3D visualization system
Mihori Kita, Yuki Mori, Sachiyo Hama Department of Ophthalmology, National Organization Kyoto Medical Center, Kyoto, Japan Purpose: To introduce a hybrid wide-angle viewing-endoscopic vitrectomy, which we have reported, using a 3D visualization system ...
Kita M, Mori Y, Hama S
doaj
Proliferative vitreoretinopathy: current and emerging treatments
Ama Sadaka,1 Gian Paolo Giuliari2,31Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA; 2Centro de Cirugía Oftalmológica (CECOF), Caracas, Venezuela; 3Department of Ophthalmology, Domingo Luciani ...
Sadaka A, Giuliari GP
doaj
Leveraging AAV1-Rac1T17N to prevent experimental proliferative vitreoretinopathy
Background Platelet-derived growth factor receptor β (PDGFRβ) is the principal PDGFR isoform in retinal pigment epithelial (RPE) cells from the epiretinal membranes of patients with proliferative vitreoretinopathy (PVR).
Duo Li +8 more
doaj +1 more source
A sustained dual drug delivery system for proliferative vitreoretinopathy
Proliferative vitreoretinopathy (PVR) is a significant threat for vision recovery from retinal detachment or ocular trauma. Currently, no approved pharmacological intervention to prevent PVR.
Ying Xiao +7 more
doaj +1 more source
Autologous peripheral retinal pigment epithelium translocation in patients with subfoveal neovascular membranes [PDF]
AIM: To evaluate the possibility of translocating autologous peripheral retinal pigment epithelial (RPE) cells and enhance their adhesion to improve functional outcome after choroidal neovascular membrane ...
Baarsma, G.S. (Seerp) +8 more
core +3 more sources
The Role of Thrombin in Proliferative Vitreoretinopathy
To determine the role of thrombin in the development of proliferative vitreoretinopathy (PVR).Vitreous was collected from patients undergoing a vitrectomy (macular holes and puckers, n = 11 [controls]; retinal detachment without PVR development following vitrectomy, n = 15 [RRD1]; retinal detachment with PVR development within 6 months after vitrectomy,
Jeroen Bastiaans +8 more
openaire +3 more sources

